Results 111 to 120 of about 462,633 (304)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Experimental observation of transition behavior on a flat plate [PDF]
In studying transition behavior a shock tube and tunnel were used to produce high temperatures, and thin-film platinum heat gauges were used to measure local heat flux as well as to detect the transition of the laminar boundary layer over a flat plate ...
Nagamatsu, H. T.
core +1 more source
Chemically active substitutional nitrogen impurity in carbon nanotubes
, 2004 We investigate the nitrogen substitutional impurity in semiconducting zigzag and metallic armchair single-wall carbon nanotubes using ab initio density functional theory.
A. Oberlin +27 more
core +1 more source
Experimental behavior of connection between composite columns and reinforced concrete flat slab
Journal of Engineering and Applied ScienceThe combination of concrete-filled steel tube (CFST) columns and reinforced concrete flat slabs provides a suitable structural solution that can be used to replace traditional structures in high-rise buildings.
Mohamed Yousry +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Measurements in the turbulent boundary layer at constant pressure in subsonic and supersonic flow. Part 1: Mean flow [PDF]
Experiments were carried out to test the accuracy of laser Doppler instrumentation for measurement of Reynolds stresses in turbulent boundary layers in supersonic flow. Two facilities were used to study flow at constant pressure.
Coles, D. E. +2 more
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
International Journal of ThermofluidsThe present work focuses on the analysis of heat transfer and flow characteristics in a horizontal spiral coil with rectangular ribbed flat tubes. The influence of Reynolds numbers (Re) ranging from 3000 to 12,000, relative rib height (Hn) from 0.04 to 0.
Luan Nguyen Thanh, Minh Ha Nguyen
doaj +1 more source