Results 61 to 70 of about 106,281 (264)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Stability of flat tube SOFC stack with CH4/CO2 direct internal reforming
工程科学学报Solid oxide fuel cells (SOFCs) are highly efficient and eco-friendly energy conversion devices that can utilize hydrocarbon fuels such as natural gas and biogas.
Yangguang FENG +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Case Studies in Thermal EngineeringIn this study, a numerical analysis was performed to investigate how the aspect ratio of flat tubes in a double-tube latent thermal energy storage system affects the melting behavior and thermal transfer properties of N-eicosane.
Gwan Gyu Kim +5 more
doaj +1 more source
The comparison of air flow LDA measurement in simple cylindrical and cylindrical tube with flat external wall [PDF]
FME Transactions, 2013 The application of 2D laser Doppler anemometry systems is considered, in the case of fluid flow confined in simple cylindrical and in cylindrical tube with flat external surface of the wall. Geometric optics laws are applied to the central lines of laser
Ilić Jelena T. +4 more
doaj
A Review of Airside Heat Transfer Augmentation with Vortex Generators on Heat Transfer Surface
Energies, 2018 Heat exchanger performance can be improved via the introduction of vortex generators to the airside surface, based on the mechanism that the generated longitudinal vortices can disrupt the boundary layer growth, increase the turbulence intensity and ...
Lei Chai, Savvas A. Tassou
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
AIP Advances, 2012 This paper describes the increase in surface energy of substrates by their treatment with gas composition generated in plasmas of DBD (Dielectric Barrier Discharge) in O2 admixed with N2.
E. V. Shun'ko, V. S. Belkin
doaj +1 more source