Results 81 to 90 of about 462,633 (304)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Wearable fluid power composed of transformed flat tube actuators [PDF]

IEEE/RSJ International Conference on Intelligent Robots and System, 2003
This paper presents a novel approach of driving the human joints by means of a fluid control system with flexibility just like clothes, which leads to a cyborg amplifying the human motor function. Former actuators for body mounting were not always designed from the point of clothing comfort.
H.Tsukagoshi, A.Kitagawa, Y.Kamata
openaire   +1 more source

Large-Eddy Simulations of Flow and Heat Transfer in Complex Three-Dimensional Multilouvered Fins [PDF]

, 2000
The paper describes the computational procedure and results from large-eddy simulations in a complex three-dimensional louver geometry. The three-dimensionality in the louver geometry occurs along the height of the fin, where the angled louver ...
Huang, W., Tafti, D.K., Wang, G., Zhang, X.   +3 more
core  

Fabrication and transport properties of Sr0.6K0.4Fe2As2 multifilamentary superconducting wires

, 2012
Seven-core Ag/Fe sheathed Sr0.6K0.4Fe2As2 (Sr-122) superconducting wires were produced by the ex situ powder-in-tube (PIT) method. The relationship between the cold-work deformation process and the superconducting properties of wires were systematically ...
Lin, He, Ma, Yanwei, Wang, Chengduo, Wang, Chunlei, Wang, Dongliang, Yao, Chao, Zhang, Qianjun, Zhang, Xianping   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stability of flat tube SOFC stack with CH4/CO2 direct internal reforming

工程科学学报
Solid oxide fuel cells (SOFCs) are highly efficient and eco-friendly energy conversion devices that can utilize hydrocarbon fuels such as natural gas and biogas.
Yangguang FENG, Kedi LIN, Yang ZHANG, Wanglin LIN, Wanbing GUAN   +4 more
doaj   +1 more source

Environmental test report for the WX-32335 SEC camera tube [PDF]

The environmental testing activity on the WX-32335 was carried out to determine if this tube type could withstand the environmental requirements established for the International Ultraviolet Explorer (IUE) camera tube (WX-32224). The results of the tests
Malanoski, R. J.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The comparison of air flow LDA measurement in simple cylindrical and cylindrical tube with flat external wall [PDF]

FME Transactions, 2013
The application of 2D laser Doppler anemometry systems is considered, in the case of fluid flow confined in simple cylindrical and in cylindrical tube with flat external surface of the wall. Geometric optics laws are applied to the central lines of laser
Ilić Jelena T., Ristić Slavica S., Čantrak Đorđe S., Janković Novica Z., Srećković Milesa Ž.   +4 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source