Results 61 to 70 of about 13,343,024 (267)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

From World Development Indicators

open access: yes, 2017
The Atlas of Sustainable Development Goals 2017 uses maps, charts and analysis to illustrate, trends, challenges and measurement issues related to each of the 17 Sustainable Development Goals.
World Bank
core   +1 more source

Hair smoothing treatments: Perceptions and wrong practices among females in Saudi Arabia

open access: yesJournal of Dermatology and Dermatologic Surgery, 2019
Introduction: In the last few years, smoothing hair treatments has taken the Saudi cosmetic industry by storm, all containing various levels of formaldehyde, a classified carcinogen by The World Health Organization (WHO), International Agency for ...
Bushra Algarni   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Savoirs locaux: partage des connaissances entre l'Afrique de l'Est et l'Asie du Sud : Un exemple de cooperation Sud-Sud

open access: yes, 2003
Inspired by the success of the pilot study tour, the Africa Region embarked on an initiative to build cross-regional partnership between East Africa and South Asia seeking to integrate indigenous knowledge and
World Bank
core   +1 more source

Managing and governing commodity chains: the role of producer service firms in the secondary global city of Hamburg

open access: yesDIE ERDE: Journal of the Geographical Society of Berlin, 2015
This paper is motivated by the observation that our understanding of global cities in Germany and beyond is limited because the practices through which producer service firms (PSFs) are involved in managing and governing their clients’ global commodity ...
Parnreiter, Christof
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

CauseKG: A Framework Enhancing Causal Inference With Implicit Knowledge Deduced From Knowledge Graphs

open access: yesIEEE Access
Causal inference is a critical technique for inferring causal relationships from data and distinguishing causation from correlation. Causal inference frameworks rely on structured data, typically represented in flat tables or relational models.
Hao Huang, Maria-Esther Vidal
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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