Results 141 to 150 of about 77,472 (265)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Intracavitary Drainage Followed by Lobectomy for a Giant Bulla Causing Respiratory Failure due to Severe Mediastinal Compression: A Case Report. [PDF]

Surg Case Rep
Tokutake H, Wada H, Onozato Y, Kamata T, Anayama T, Yoshino I, Yoshida S.   +6 more
europepmc   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Planning-Based Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy (Flattened Versus Unflattened Beams), Intensity-Modulated Radiotherapy, and Volumetric Modulated Arc Therapy for Pituitary Adenomas on Halcyon. [PDF]

Cureus
Malik D, Prasath NV, Chinnamuthu M, Mahajan R, Rajendiran G, Bagdare P.   +5 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Two Cases of Oculomotor Nerve Palsy in Idiopathic Intracranial Hypertension and a Literature Review. [PDF]

Case Rep Neurol Med
Patel PA, Muppa J, Giurgiutiu DV.
europepmc   +1 more source

Reconfigurable Inflatables Through Controlled Surface Crumpling

Advanced Science, EarlyView.
ABSTRACT Inflatable structures offer remarkable versatility due to their compact storage and rapid deployment, making them ideal for lightweight, quickly assembled, and deployable applications. These structures are typically made from membranes that are nearly inextensible yet highly flexible.
Yi Yang, Hye Jun Youn, Leon Kamp, Renate Sachse, Wenjie Li, Jose Vidal, Jin Feng, Martin Bechthold, Katia Bertoldi   +8 more
wiley   +1 more source

Cervical flexion-induced myelopathy (Hirayama disease): A radiology case report. [PDF]

Radiol Case Rep
Ulaganathan B, Pandian ASP, Sellamuthu E, Jayagurunathan U.   +3 more
europepmc   +1 more source

Defect Driven Electronic Structure Reconfiguration and Hierarchical Phonon Suppression in Ag2Se Thermoelectrics

Advanced Science, EarlyView.
Indium substitution in Ag2Se nanocrystals simultaneously tailors electronic structure and lattice dynamics. Fermi‐level upshift and band‐gap narrowing enhance electrical transport, while defect‐induced lattice softening intensifies phonon scattering and suppresses lattice thermal conductivity.
Yineng Gou, Mengyao Li, Fang Lyu, Xiaolong Sun, Muyang Huang, Wenhao Xie, Liangwei Hu, Wei Cao, Yue Hou, Yong Liu, Andreu Cabot, Ziyu Wang   +11 more
wiley   +1 more source

Radiographic evaluation of degenerative findings in the temporomandibular joint using CBCT: a prevalence-based study. [PDF]

BMC Oral Health
Öçal MÇ, Daldal M, Baybars SC, Katı E.   +3 more
europepmc   +1 more source