Results 101 to 110 of about 15,751 (313)

Stereotactic body radiation therapy for liver tumours using flattening filter free beam: dosimetric and technical considerations

Radiation Oncology, 2012
Purpose To report the initial institute experience in terms of dosimetric and technical aspects in stereotactic body radiation therapy (SBRT) delivered using flattening filter free (FFF) beam in patients with liver lesions.
Mancosu Pietro, Castiglioni Simona, Reggiori Giacomo, Catalano Maddalena, Alongi Filippo, Pellegrini Chiara, Arcangeli Stefano, Tozzi Angelo, Lobefalo Francesca, Fogliata Antonella, Navarria Piera, Cozzi Luca, Scorsetti Marta   +12 more
doaj   +1 more source

A Monte Carlo study of a flattening filter-free linear accelerator verified with measurements. [PDF]

, 2010
A Monte Carlo model of an Elekta Precise linear accelerator has been built and verified by measured data for a 6 and 10 MV photon beam running with and without a flattening filter in the beam line.
Dalaryd, Mårten, Wetterstedt, Sacha Af, Wieslander, Elinore,, Ceberg, Crister,, Kragl, Gabriele, Elinore Wieslander, Wetterstedt, Sacha Af,, Tommy Knöös, Wieslander, Elinore, Dietmar Georg, Brendan McClean, Sacha af Wetterstedt, Georg, Dietmar, Mårten Dalaryd, Crister Ceberg, Knöös, Tommy, Gabriele Kragl, McClean, Brendan, Ceberg, Crister, Lund University., Knöös, Tommy,   +20 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

A modification of flattening filter free linac for IMRT [PDF]

, 2011
Purpose: This study investigates the benefits of a modified flattening filter free (FFF) linac over the standard (STD) linac equipped with the flattening filter. Energy and angular spread of the electron beam of the FFF linac were modified.
M. Makrigiorgos, Seco, J., P. Tsiamas, Z. Han, Bhagwat, M., K. Theodorou, Theodorou, K., J. Maddox, J. Seco, Zygmanski, P., P. Zygmanski, C. Kappas, Han, Z., Maddox, J., Tsiamas, P., Kappas, C., Makrigiorgos, M., K. Marcus, M. Bhagwat, Marcus, K.   +19 more
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

The effect of flattened and unflattened beams on apoptotic, tumor suppressor, and cell proliferation gene expression levels in preclinical malignant melanoma radiotherapy

Laboratuvar Hayvanları Bilimi ve Uygulamaları Dergisi
Background/aim: The current evidence base remains lacking regarding the differences in radiobiological outcomes dependent on the presence of a flattening filter in malignant melanoma cancer (MMe Ca) radiotherapy.
Engin Sümer, Serhat Aras, Tuğba Kul Köprülü, Alperen Tuncer   +3 more
doaj   +1 more source

Dosimetric effects of removing the flattening filter in radiotherapy treatment units [Elektronisk resurs] [PDF]

, 2015
Popular Abstract in Swedish Vid extern strålbehandling används en s.k. linjäraccelerator för att producera och leverera den önskade strålningen till cancertumörer.
Dalaryd, Mårten,, Lund University.
core  

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Stereotactic body radiotherapy for early-stage lung cancer: a systematic review on the choice of photon energy and linac flattened/unflattened beams

Radiation Oncology
SBRT is an effective local treatment for patients with early-stage non-small cell lung cancer (NSCLC). This treatment is currently used in patients who have poor lung function or who decline surgery.
Ashlesha Gill, Andrew L Hirst, Pejman Rowshanfarzad, Suki Gill, Nicholas Bucknell, Joshua Dass, Mahsheed Sabet   +6 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source