Results 161 to 170 of about 68,853 (304)
Flavivirus Receptors: Diversity, Identity, and Cell Entry
Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for significant mortality and morbidity worldwide. The genus comprises more than seventy small, positive-sense, single-stranded RNA viruses, which are responsible for a ...
M. Lauréti +4 more
semanticscholar +1 more source
The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia
ABSTRACT As the climate of Asia changes under the influence of global warming, the incidence and spatial distribution of known zoonoses will evolve, and new zoonoses are expected to emerge as a result of greater exposure to organisms which currently occur only in wildlife.
Roger S. Morris, Masako Wada
wiley +1 more source
Structures and mechanisms in flavivirus fusion
This chapter focuses on the work carried out with tick-borne encephalitis (TBE) virus, the structurally best characterized of the flaviviruses. The data is related to those obtained with other flaviviruses, which are assumed to have a conserved structural organization, and compare the characteristics of flavivirus fusion to those of other enveloped ...
Franz X. Heinz, Steven L. Allison
openaire +3 more sources
Significance Mosquito-transmitted flaviviruses such as Zika virus (ZIKV) are responsible for over 400 million human infections each year. Unfortunately, the molecular mechanisms that facilitate flavivirus transmission by mosquitoes remain unclear.
Giel P Göertz +12 more
semanticscholar +1 more source
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan +16 more
wiley +1 more source
Complement receptor mediates enhanced flavivirus replication in macrophages. [PDF]
Mary Jane Cardosa +2 more
openalex +1 more source
Serum‐Free Japanese Encephalitis Virus Production in a Single‐Use Fixed‐Bed Bioreactor
ABSTRACT Fixed‐bed bioreactors for anchorage‐dependent cells are an obvious choice for development because of their large‐scale capabilities, allowing manufacturing with reduced cost and footprint. In this study, a serum‐free production process for Japanese encephalitis virus (JEV) in a single‐use fixed‐bed bioreactor was developed and compared to ...
Marco Kress +2 more
wiley +1 more source
The Sweet Aspects of Orthoflavivirus Treatment Design and Vaccine Development
ABSTRACT Viruses in the genus Orthoflavivirus are among the most important human pathogens because of their significant public health impact. Many strategies have been proposed to develop specific or broad‐spectrum treatments and preventive measures for these viral infections in humans.
Ana C. Alcalá +2 more
wiley +1 more source
Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen
Background The genus Flavivirus encompasses more than 50 distinct species of arthropod-borne viruses, including several major human pathogens, such as West Nile virus, yellow fever virus, Japanese encephalitis virus and the four serotypes of dengue ...
Canard Bruno +9 more
doaj +1 more source
Enhanced Neutralization of Flavivirus by Monoclonal Antibodies against Negishi Virus [PDF]
Yukage Motohide +2 more
openalex +1 more source

