Results 241 to 250 of about 45,475 (259)

Flavivirus Entry Inhibitors

ACS Infectious Diseases, 2015
Many flaviviruses are significant human pathogens that are transmitted by mosquitoes and ticks. Although effective vaccines are available for yellow fever virus, Japanese encephalitic virus, and tick-borne encephalitis virus, these and other flaviviruses still cause thousands of human deaths and millions of illnesses each year.
Qing Yin Wang, Pei Yong Shi
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Flavivirus Entry Inhibitors

2022
Flaviviruses, including Dengue virus, Zika virus, Yellow fever virus, Japanese encephalitis virus, West Nile virus, cause thousands of deaths and millions of illnesses each year. The large outbreak of ZIKV in 2016 reminds us that flaviviruses can pose a serious threat to human safety and public health as emerging and re-emerging viruses. However, there
Yufeng, Yu, Lulu, Si, Yu, Meng
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Immunopathology of flavivirus infections

Immunology & Cell Biology, 2006
With the recent emergence of the flavivirus, West Nile virus (WNV), in particular, the New York strain of Lineage I WNV in North America in 1999, there has been a significant increase in activity in neurotropic flavivirus research. These viruses cause encephalitis that can result in permanent neurological sequelae or death. Attempts to develop vaccines
Meghann Teague Getts, Bimmi Shrestha, Sabita Rana, Nicholas J. C. King, Alison M. Kesson, Daniel R. Getts   +5 more
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Flavivirus vaccines

Vaccine, 1988
Diseases caused by flavivirus infection have been a scourge of mankind for over three centuries; with yellow fever, dengue fever and Russian spring-summer encephalitis causing epidemics resulting in thousands of fatalities. Due to the development of a safe and efficacious live-attenuated vaccine against yellow fever, this disease is no longer such a ...
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Flaviviruses and flavivirus vaccines

Vaccine, 2012
Several human-pathogenic flaviviruses (including yellow fever, dengue, Japanese encephalitis, West Nile and tick-borne encephalitis viruses) have a significant public health impact in different parts of the world and the potential of emerging in previously non-endemic regions.
Franz X. Heinz, Karin Stiasny
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Platelets in the pathogenesis of flavivirus disease

Current Opinion in Virology, 2022
Research on the role of platelets in modulating innate and adaptive host immune responses has gaining importance in the last two decades. Since the virus can directly interact with platelet receptors and modulate the host immune response, understanding the role of platelets in viral pathogenesis would pave way for novel therapeutic means.
Agiesh Kumar Balakrishna Pillai, Justin Jang Hann Chu, Vignesh Mariappan, Aashika Raagavi JeanPierre   +3 more
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Recombination and flavivirus vaccines: a commentary

Vaccine, 2005
A review article recently appeared in the Lancet by Seligman and Gould, in which the authors raise a safety concern for flavivirus vaccines based on possible recombination between wild-type viruses and live, attenuated vaccine viruses. Flaviviruses are small enveloped viruses with a single positive sense RNA genome containing a single long open reading
Monath, Thomas P., Kanesa-thasan, Niranjan, Guirakhoo, Farshad, Pugachev, Konstantin, Almond, Jeffrey, Lang, Jean, Quentin-Millet, Marie-Jose, Barrett, Alan D. T., Brinton, Margo A., Cetron, Martin S., Barwick, Rachel S., Chambers, Thomas J., Halstead, Scott B., Roehrig, John T., Kinney, Richard M., Rico-Hesse, Rebecca, Strauss, James H.   +16 more
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Microscopy techniques in flavivirus research

Micron, 2014
The Flavivirus genus is composed of many medically important viruses that cause high morbidity and mortality, which include Dengue and West Nile viruses. Various molecular and biochemical techniques have been developed in the endeavour to study flaviviruses.
Mun Keat Chong, Anthony Jin Shun Chua, Terence Tze Tong Tan, Suat Hoon Tan, Mah Lee Ng   +4 more
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Dynamics of Flavivirus Infection in Mosquitoes

2003
Abstract Mosquito-borne flaviviruses are emerging as the cause of some of the most serious and widespread arthropod-borne viral diseases in the world. Flavivirus outbreaks are influenced by intrinsic (e.g., viral strain, vector competence, host susceptibility) and extrinsic (e.g., temperature, rainfall, human land use) factors that affect mosquito ...
Laura D. Kramer, Gregory D. Ebel
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