Results 21 to 30 of about 856,468 (203)
International Journal of Behavioral Nutrition and Physical Activity, 2021 Physical activity (PA) and sedentary behaviour (SB) of pre-school aged children are associated with important health and developmental outcomes. Accurate measurement of these behaviours in young children is critical for research and practice in this area.
Sophie M. Phillips +6 more
doaj +1 more source
Evolution of Orthodontic Aligners – A Narrative Review
Dentistry and Medical ResearchClear aligners seem to be a new modality for patients undergoing orthodontic treatment; the initial concept of this treatment evolved in the 20th century.
Trupti Shankar Nakhate +5 more
doaj +3 more sources
Towards Intelligent Databases [PDF]
, 1993 This article is a presentation of the objectives and techniques of deductive databases. The deductive approach to databases aims at extending with intensional definitions other database paradigms that describe applications extensionaUy.
Bry, François +2 more
core +1 more source
Development of a Tool for the Analysis of Plant Stress Proteins [PDF]
International Journal Bioautomation, 2011 The recent explosion of biological data and the accompaniment proliferation of distributed databases make it challenging for biologists and bioinformatists to discover the best and concise data resources for their needs, and the most efficient way to ...
Muhammad Ali +3 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Network-Pharmacology-Based Mechanism Elucidation and Validation for Phytochemicals from Artemisia Vestita Against Osteoarthritis [PDF]
Iranian Journal of Chemistry & Chemical EngineeringThe objective of this study was to utilize network pharmacology and bioinformatics tools to identify and assess bioactive compounds derived from Artemisia vestita for their potential therapeutic use in osteoarthritis (OA).
Chen Jiang, Yongheng Liu, Hui Xu
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2012 Bij herhaling roepen werkgevers om flex, flex en nog meer flex. De argumenten: minder kosten voor werkgevers, (ont)slagvaardiger personeelsbeleid, met als doel meer concurrentiekracht op het toneel van de ...
Popma, J.
core +2 more sources
A Comparison of Quality of Care in Critical Access Hospitals and Other Rural Hospitals
Online Journal of Rural Nursing and Health Care, 2014 Purpose: The United States has about 2100 rural hospitals. Approximately 1300 are Critical Access Hospitals (CAHs) with 25 beds or less. CAHs receive cost-based reimbursement through the federal Flex program with the goal to improve quality and access ...
Marianne Baernholdt +4 more
doaj +1 more source