Results 21 to 30 of about 10,255 (211)
International Journal of Behavioral Nutrition and Physical Activity, 2021 Physical activity (PA) and sedentary behaviour (SB) of pre-school aged children are associated with important health and developmental outcomes. Accurate measurement of these behaviours in young children is critical for research and practice in this area.
Sophie M. Phillips +6 more
doaj +1 more source
Evolution of Orthodontic Aligners – A Narrative Review
Dentistry and Medical ResearchClear aligners seem to be a new modality for patients undergoing orthodontic treatment; the initial concept of this treatment evolved in the 20th century.
Trupti Shankar Nakhate +5 more
doaj +3 more sources
Development of a Tool for the Analysis of Plant Stress Proteins [PDF]
International Journal Bioautomation, 2011 The recent explosion of biological data and the accompaniment proliferation of distributed databases make it challenging for biologists and bioinformatists to discover the best and concise data resources for their needs, and the most efficient way to ...
Muhammad Ali +3 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Network-Pharmacology-Based Mechanism Elucidation and Validation for Phytochemicals from Artemisia Vestita Against Osteoarthritis [PDF]
Iranian Journal of Chemistry & Chemical EngineeringThe objective of this study was to utilize network pharmacology and bioinformatics tools to identify and assess bioactive compounds derived from Artemisia vestita for their potential therapeutic use in osteoarthritis (OA).
Chen Jiang, Yongheng Liu, Hui Xu
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A Comparison of Quality of Care in Critical Access Hospitals and Other Rural Hospitals
Online Journal of Rural Nursing and Health Care, 2014 Purpose: The United States has about 2100 rural hospitals. Approximately 1300 are Critical Access Hospitals (CAHs) with 25 beds or less. CAHs receive cost-based reimbursement through the federal Flex program with the goal to improve quality and access ...
Marianne Baernholdt +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source