Results 101 to 110 of about 3,280,790 (318)

Evaluating the Ranking of Performance Variables in Flexible Manufacturing System through the Best-Worst Method

open access: yesDesigns
Flexible Manufacturing Systems (FMSs) provide a competitive edge in the ever-evolving manufacturing landscape, offering the agility to swiftly adapt to changing customer demands and product lifecycles.
Anthony Bagherian   +3 more
doaj   +1 more source

Overview of Job Protected Leave [PDF]

open access: yes, 2010
An overview of job protected leave by number of employees and ...
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Waiver of Rights [PDF]

open access: yes, 2007
Part one of this memorandum provides a summary of questions asked and comments submitted in response to the DOL request for information ( RFI ) about waiver of FMLA rights.
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Rethinking housing – Design and architecture for flexible and affordable living

open access: yesAgathón
Architecture is called to face the challenges of an era marked by global change, economic instability, environmental crises, geopolitical tensions, and pandemic emergencies.
Claudia Battaino   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Agenda [PDF]

open access: yes, 2011
Agenda for the event: What an Aging Workforce Can Teach Us About Workplace Flexibility held on July 18, 2005 by Workplace Flexibility ...
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Panelist Biographies [PDF]

open access: yes, 2006
The biographies of the panelist of the Workers with Disabilities: The Role of Workplace Flexibility event held November 13 ...
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

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