Results 121 to 130 of about 5,555,251 (415)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Early Retirement Incentive Plans and the Age Discrimination in Employment Act [PDF]
, 2010 Early retirement incentive plans (ERIP) “seek to give incentives to older employees to retire before conventional retirement age. The purpose of these programs is to cut back on salaries and benefits to make way for younger workers.” While some ERIPs ...
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Getting a Grip on Cognitive Flexibility
Current Directions in Psychological Science, 2018 Cognitive flexibility refers to the ability to quickly reconfigure our mind, as when we switch between different tasks. This review highlights recent evidence showing that cognitive flexibility can be conditioned by simple incentives typically known to ...
S. Braem, T. Egner
semanticscholar +1 more source
, 2007 Part one of this memorandum provides a summary of questions asked and comments submitted in response to the DOL request for information ( RFI ) about attendance policies.
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
DesignsFlexible Manufacturing Systems (FMSs) provide a competitive edge in the ever-evolving manufacturing landscape, offering the agility to swiftly adapt to changing customer demands and product lifecycles.
Anthony Bagherian +3 more
doaj +1 more source
, 2006 The agenda of the Workers with Disabilities: The Role of Workplace Flexibility event held November 13 ...
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FMLA Leave Determinations/Medical Certifications [PDF]
, 2007 Part one of this memorandum provides a summary of questions asked and comments submitted in response to the DOL request for information ( RFI ) about FMLA leave determinations and medical certifications.
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source