Results 101 to 110 of about 4,355,972 (307)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A bionic self-driven retinomorphic eye with ionogel photosynaptic retina

Nature Communications
Bioinspired bionic eyes should be self-driving, repairable and conformal to arbitrary geometries. Such eye would enable wide-field detection and efficient visual signal processing without requiring external energy, along with retinal transplantation by ...
Xu Luo, Chen Chen, Zixi He, Min Wang, Keyuan Pan, Xuemei Dong, Zifan Li, Bin Liu, Zicheng Zhang, Yueyue Wu, Chaoyi Ban, Rong Chen, Dengfeng Zhang, Kaili Wang, Qiye Wang, Junyue Li, Gang Lu, Juqing Liu, Zhengdong Liu, Wei Huang   +19 more
doaj   +1 more source

Microsecond-Scale Transient Thermal Sensing Enabled by Flexible Mo1−xWxS2 Alloys

Research
Real-time thermal sensing through flexible temperature sensors in extreme environments is critically essential for precisely monitoring chemical reactions, propellant combustions, and metallurgy processes.
Weiwei Li, Lingyan Kong, Manzhang Xu, Jiuwei Gao, Lei Luo, Yingzhe Li, Kexin Wang, Yilin Zhou, Lei Li, Yuan Wei, Xiaoshan Zhang, Ruoqing Zhao, Mengdi Chen, Yuting Yan, Xiaoguang Luo, Zhaohe Dai, Lu Zheng, Xuewen Wang, Wei Huang   +18 more
doaj   +1 more source

Wavelength Scanning Interferometry for PV Production In-line Metrology [PDF]

, 2014
Flexible PV modules are manufactured using roll to roll (R2R) technology.
Blunt, Liam, Elrawemi, Mohamed, Fleming, Leigh, Gao, F., Muhamedsalih, Hussam   +4 more
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Induced dipole moments in amorphous ZnCdS catalysts facilitate photocatalytic H2 evolution

Nature Communications
Amorphous semiconductors without perfect crystalline lattice structures are usually considered to be unfavorable for photocatalysis due to the presence of enriched trap states and defects.
Xin Wang, Boyan Liu, Siqing Ma, Yingjuan Zhang, Lianzhou Wang, Gangqiang Zhu, Wei Huang, Songcan Wang   +7 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Heterointeraction-Induced Nucleation Promoting Vertical Growth and Suppressing Phase Separation for Efficient Wide-Bandgap Perovskite Solar Cells and Tandem Devices

Research
As a key component of perovskite-based tandem photovoltaic devices, wide-bandgap (WBG) perovskite solar cells (PSCs) have been extensively explored recently.
Changbo Li, Yuyi Wang, Weiyin Gao, Jianxiong Yang, Zelin Wang, Xiaojia Zhao, Xinyuan Liu, Liangxu Wang, Yile Liu, Xiaobo Wang, He Dong, Long Zhou, Weidong Zhu, Chenxin Ran, Wei Huang   +14 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Composite Flexible Blanket Insulation [PDF]

, 1991
Composite flexible multilayer insulation systems (MLI) were evaluated for thermal performance and compared with the currently used fibrous silica (baseline) insulation system.
Goldstein, Howard E., Kourtides, Demetrius A., Pitts, William C., Sawko, Paul M.   +3 more
core   +1 more source