Results 41 to 50 of about 4,355,972 (307)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Lateral fligh control design for a highly flexible aircraft using a nonsmooth method [PDF]
This paper describes a nonsmooth optimization technique for designing a lateral flight control law for a highly flexible aircraft. Flexible modes and high-dimensional models pose a major challenge to modern control design tools.
Alazard, Daniel +3 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Short-range charge transfer for efficient ultra-narrowband deep blue afterglow
Efficient and narrowband blue organic afterglow materials are critical components for advanced optoelectronic applications, but so far, have been rarely explored. Herein, we report short-range charge transfer-assisted high efficiency and ultra-narrowband
Xin Zou +8 more
doaj +1 more source
High performance flexible Sn-Pb mixed perovskite solar cells enabled by a crosslinking additive
Flexible perovskite solar cells (PSCs) have drawn increasing attention due to their promising applications for wearable electronics and aerospace applications.
Ya Li +10 more
doaj +1 more source
Synchronization of flexible sheets
When swimming in close proximity, some microorganisms such as spermatozoa synchronize their flagella. Previous work on swimming sheets showed that such synchronization requires a geometrical asymmetry in the flagellar waveforms.
Elfring, Gwynn J., Lauga, Eric
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Phototheranostics as an advanced approach involved in exogenous light‐mediated diagnosis and treatment techniques has attracted broad attention in interdisciplinary biomedical applications.
Bo Wang +4 more
doaj +1 more source
Flexible Weinstein manifolds [PDF]
This survey on flexible Weinstein manifolds is, essentially, an extract from our recent joint book.Comment: 41 pages, 8 ...
Kai Cieliebak +2 more
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