Results 61 to 70 of about 1,468,047 (317)

Flexible ureteroscopy for upper tract urothelial carcinoma

open access: yes, 2022
Flexible ureteroscopy (fURS) is an essential tool for the diagnosis, risk stratification, and treatment of upper tract urothelial carcinoma (UTUC). fURS should actually be performed in case of uncertainty, for kidney-sparing surgery (KSS), and even ...
Gontero, Paolo   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Nature-Inspired Structural Materials for Flexible Electronic Devices

open access: yes, 2017
Exciting advancements have been made in the field of flexible electronic devices in the last two decades and will certainly lead to a revolution in peoples’ lives in the future.
Chen, Xiaodong   +9 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Conformal 3D Li/Li13Sn5 Scaffolds Anodes for High‐Areal Energy Density Flexible Lithium Metal Batteries

open access: yesAdvanced Science
Achieving a high depth of discharge (DOD) in lithium metal anodes (LMAs) is crucial for developing high areal energy density batteries suitable for wearable electronics.
Xiaomei Huo   +5 more
doaj   +1 more source

A flexible display system for embedded applications [PDF]

open access: yes, 2013
textFlat electronic displays are ubiquitous in our environment from small handheld devices to large HDTVs. This report documents the design and development of a flexible electronic display system for low cost embedded applications. The main use of such a
Slowik, Matthew Caldwell
core  

Decision Flexibility

open access: yesCoRR, 2013
The development of new methods and representations for temporal decision-making requires a principled basis for characterizing and measuring the flexibility of decision strategies in the face of uncertainty. Our goal in this paper is to provide a framework - not a theory - for observing how decision policies behave in the face of informational ...
Tom Chávez, Ross D. Shachter
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Flexible Fertigungssysteme Vortraege, Arbeitsplatzbeschreibungen

open access: yes, 1983
SIGLETIB: RO 4301 (1983)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Stuttgart Univ. (Germany). Sonderforschungsbereich 155 - Fertigungstechnik - Flexible Fertigungssysteme   +2 more
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

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