Results 81 to 90 of about 4,379,633 (308)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Scalable Manufacturing of Large-Area Pressure Sensor Array for Sitting Posture Recognition in Real Time

ACS Materials Au, 2023
Lu Zheng, Xuemin Hou, Manzhang Xu, Yabao Yang, Jiuwei Gao, Lei Luo, Qixuan Zhu, Weiwei Li, Xuewen Wang   +8 more
doaj   +1 more source

3D printed chitosan-based flexible electrode with antimicrobial properties for electrical stimulation therapy in wound healing

Supramolecular Materials
Enhanced bioelectrical stimulation near wound sites plays a crucial role in promoting the wound healing cascade, such as, supporting regular collagen deposition, proper extracellular matrix (ECM) remodeling.
Moses Kumi, Zishuo Hou, Yibo Zhang, Yutian Yang, Chang Han, Tengjiao Wang, Peng Li   +6 more
doaj   +1 more source

Subflexible symplectic manifolds

, 2017
We introduce a class of Weinstein domains which are sublevel sets of flexible Weinstein manifolds but are not themselves flexible. These manifolds exhibit rather subtle behavior with respect to both holomorphic curve invariants and symplectic flexibility.
Murphy, Emmy, Siegel, Kyler
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Radical-enhanced photo-activated ultralong organic phosphorescence

Nature Communications
Stimuli-responsive ultralong room temperature phosphorescence materials have attracted great attention due to their great potential in a wide variety of advanced applications.
Yuefei Wang, Zaiyong Zhang, Huanyu Yang, Shunjie Li, Xiaokang Yao, Huili Ma, Shengchen Yang, Suzhi Cai, Zhongfu An, Wei Huang   +9 more
doaj   +1 more source

Flexible thermal apparatus for mounting of thermoelectric cooler [PDF]

, 1991
A flexible heat transfer apparatus used to flexibly connect and thermally couple a thermoelectric cooler to an object to be cooled is disclosed. The flexible heat transfer apparatus consists of a pair of flexible corrugated sheets made from high thermal ...
Bard, Steven, Jones, Jack A., Petrick, S. Walter   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Semiconducting Open‐Shell Radicals for Precise Tumor Activatable Phototheranostics

Advanced Science
Semiconducting open‐shell radicals (SORs) have promising potential for the development of phototheranostic agents, enabling tumor bioimaging and boosting tumorous reactive oxygen species (ROS). Herein, a new class of semiconducting perylene diimide (PDI),
Jie Zhang, Haifen Luo, Wen Ma, Jingqi Lv, Bo Wang, Fengwei Sun, Weijie Chi, Zhuting Fang, Zhen Yang   +8 more
doaj   +1 more source

Wavelength Scanning Interferometry for PV Production In-line Metrology [PDF]

, 2014
Flexible PV modules are manufactured using roll to roll (R2R) technology.
Blunt, Liam, Elrawemi, Mohamed, Fleming, Leigh, Gao, F., Muhamedsalih, Hussam   +4 more
core