Results 51 to 60 of about 21,652 (255)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Simulation Analysis and Modeling of New Type Cam Mechanism based on Pro / E and ADAMS

open access: yesJixie chuandong, 2016
The virtual prototyping modeling of new typed disc cam mechanism with straight moving negative radius roller follower is created by using Pro / E and ADAMS.
He Haiqin, Li Yanping, Chang Yong
doaj  

Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile.

open access: yesPLoS ONE, 2019
BackgroundGlaucoma is the leading cause of irreversible blindness worldwide. It is a heterogeneous group of conditions with a common optic neuropathy and associated loss of peripheral vision.
Ian J C MacCormick   +10 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Global Dynamics of Shaft Lines Rotating in Surrounding Fluids Application to Thin Fluid Films

open access: yesInternational Journal of Rotating Machinery, 2004
While often sufficiently accurate, approaches using rotor dynamics and bladed disc dynamics are not adapted to the study of certain important cases, i.e., when observing wheel/shaft coupling or when fluid elements are strongly coupled with local ...
David Lornage   +1 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

平行不对中梅花弹性联轴器力学状态研究

open access: yesJixie chuandong, 2014
According to the parallel misalignment conditions of plum-shaped flexible coupling during working,the force physical modeling of petals of plum-shaped flexible coupling based on the radial simple shear and tangential simple compression is built.The ...
杨超, 张敬彩, 刘红旗
doaj  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc

open access: yesScientific Reports, 2017
The Miniaturised Lab-on-a-Disc (miniLOAD) platform, which utilises surface acoustic waves (SAWs) to drive the rotation of thin millimeter-scale discs on which microchannels can be fabricated and hence microfluidic operations can be performed, offers the ...
Ming K. Tan   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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