Results 31 to 40 of about 21,652 (255)
There is a complex dynamic interaction between the aero-engine bearing and the rotor, and the resulting time-varying system parameters have an impact on the nonlinear dynamic characteristics of the rolling bearing-flexible rotor system.
Renzhen Chen +5 more
doaj +1 more source
Carbon dioxide rebreathing caused by deformed silicon leaflet in the expiratory unidirectional valve
Rebreathing of carbon dioxide caused by incompetent ′cage and disc′ unidirectional valves has been reported earlier. Some manufacturers have changed the design of unidirectional valves to ′flexible leaflets′.
Arumugam Vasudevan +3 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Stresses and Displacements in an Elliptically Perforated Circular Disc Under Radial Pressure
The complex potentials governing the elastic equilibrium of a finite circular disc, elliptically perforated at its center, are obtained using Muskhelishvili’s formulation.
Christos F. MARKIDES +1 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
NATURAL FREQUENCIES OF TUNED AND MISTUNED BLADED DISCS ON A SHAFT
The dynamic behaviour of a rotor consisting of two tuned and mistuned bladed discs on a solid shaft is considered. The effect of the shaft’s flexibility on the dynamic characteristics of the bladed discs and the coupling effects between the shaft and ...
ROMUALD RZĄDKOWSKI +2 more
doaj
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Disc-Pole Assignment for Robust Control of Flexible Structures.
This paper presents a method of disc-pole assignment for the design of robust control of flexible structures. The proposed method achieves a pole assignment of the controlled modes to a specified circular region in the complex plane and simultaneously obtains robust stability of the closed-loop system for important residual modes.
OKUBO, Hiroshi, ZENIYA, Susumu
openaire +2 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source

