Results 31 to 40 of about 108,568 (327)

Research on a New Type of Rigid-Flexible Coupling 3-DOF Micro-Positioning Platform

Micromachines, 2020
A new type of rigid-flexible coupling three degrees of freedom (3-DOF) micro-positioning platform with high positioning accuracy and high bearing capacity is developed, which consists of flexible drive mechanism and rigid platform.
Guilian Wang, Yong Wang, Bingrui Lv, Ruopeng Ma, Li Liu   +4 more
doaj   +1 more source

Development of a Novel Piezoelectric Actuator Based on Stick–Slip Principle by Using Asymmetric Constraint

Micromachines, 2023
In this work, a novel piezoelectric actuator based on the stick–slip principle is proposed. The actuator is constrained by an asymmetric constraint approach; the driving foot produces lateral and longitudinal coupling displacements when the piezo stack ...
Liang Wang, Heran Wang, Junxiang Jiang, Tianwen Luo   +3 more
doaj   +1 more source

FlexOracle: predicting flexible hinges by identification of stable domains [PDF]

BMC Bioinformatics, 2007
Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions involve hinge bending. For these proteins, the accurate identification of flexible hinges connecting rigid domains would provide significant insight into motion.
Samuel Flores, Mark Gerstein
openaire   +3 more sources

A Novel Monopolar Cross-Scale Nanopositioning Stage Based on Dual Piezoelectric Stick-Slip Driving Principle

Micromachines, 2022
The precise characterization and measurement of new nanomaterials and nano devices require in situ SEM nanorobotic instrumentation systems, which put forward further technical requirements on nanopositioning techniques of compact structure, cross-scale ...
Junhui Zhu, Siyuan Meng, Yong Wang, Ming Pang, Zhiping Hu, Changhai Ru   +5 more
doaj   +1 more source

Optimal Design for 3-PSS Flexible Parallel Micromanipulator Based on Kinematic and Dynamic Characteristics

Micromachines, 2022
This paper proposes two optimal design schemes for improving the kinematic and dynamic performance of the 3-PSS flexible parallel micromanipulator according to different application requirements and conditions.
Jun Ren, Qiliang Li, Hanhai Wu, Qiuyu Cao   +3 more
doaj   +1 more source

Stress Dispersion Design in Continuum Compliant Structure toward Multi-DOF Endoluminal Forceps

Applied Sciences, 2022
Gastrointestinal cancer, when detected early, is treated by accessing the lesion through the natural orifice using flexible endoscopes. However, the limited degree-of-freedom (DOF) of conventional treatment devices and the narrow surgical view through ...
Keisuke Osawa, D. S. V. Bandara, Ryu Nakadate, Yoshihiro Nagao, Tomohiko Akahoshi, Masatoshi Eto, Jumpei Arata   +6 more
doaj   +1 more source

Design and Performance Research of a Precision Micro-Drive Reduction System without Additional Motion

Micromachines, 2022
A micro-drive system is a key part of macro-micro-drive technology and precision positioning technology in which a micro-drive reduction system can provide more precise motion and suitable small space motion. Therefore, it is necessary to study precision
Manzhi Yang, Xiaodong Zhang, Chuanwei Zhang, Hongzhang Wu, Yizhi Yang   +4 more
doaj   +1 more source

Divergent evolution of protein conformational dynamics in dihydrofolate reductase. [PDF]

, 2013
Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the ...
Bhabha, Gira, Dyson, H Jane, Ekiert, Damian C, Godzik, Adam, Jennewein, Madeleine, Kroon, Gerard, Tuttle, Lisa M, Wilson, Ian A, Wright, Peter E, Zmasek, Christian M   +9 more
core   +2 more sources

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

eLife, 2023
To address the ongoing SARS-CoV-2 pandemic and prepare for future coronavirus outbreaks, understanding the protective potential of epitopes conserved across SARS-CoV-2 variants and coronavirus lineages is essential.
Rui P Silva, Yimin Huang, Annalee W Nguyen, Ching-Lin Hsieh, Oladimeji S Olaluwoye, Tamer S Kaoud, Rebecca E Wilen, Ahlam N Qerqez, Jun-Gyu Park, Ahmed M Khalil, Laura R Azouz, Kevin C Le, Amanda L Bohanon, Andrea M DiVenere, Yutong Liu, Alison G Lee, Dzifa A Amengor, Sophie R Shoemaker, Shawn M Costello, Eduardo A Padlan, Susan Marqusee, Luis Martinez-Sobrido, Kevin N Dalby, Sheena D'Arcy, Jason S McLellan, Jennifer A Maynard   +25 more
doaj   +1 more source

Investigation of sequence features of hinge-bending regions in proteins with domain movements using kernel logistic regression [PDF]

, 2020
Background: Hinge-bending movements in proteins comprising two or more domains form a large class of functional movements. Hinge-bending regions demarcate protein domains and collectively control the domain movement.
Cawley, Gavin, Hayward, Steven, Veevers, Ruth   +2 more
core   +1 more source