Results 51 to 60 of about 5,453 (298)

Flexible job-shop scheduling problem with parallel batch machines based on an enhanced multi-population genetic algorithm

open access: yesComplex & Intelligent Systems
The flexible job-shop scheduling problem (FJSP) with parallel batch processing machine (PBM) is one of those long-standing issues that needs cutting-edge approaches. It is a recent extension of standard flexible job shop scheduling problems.
Lirui Xue   +3 more
doaj   +1 more source

Um modelo para o planejamento e a programação da produção em ambientes job shop baseado em redes de Petri [PDF]

open access: yes, 2001
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de ProduçãoUm dos maiores desafios enfrentados pela administração da produção e do qual depende muito a eficiência de todo sistema ...
Chile Palomino, Reynaldo
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Flexible job shop scheduling using genetic algorithm and heuristic rules

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
Job shop scheduling with the availability of more than one machine to perform an operation, also known as the flexible job shop scheduling problem, is computationally NP-hard.
Parinya KAWEEGITBUNDIT, Toru EGUCHI
doaj   +1 more source

Flexible job-shop scheduling with transportation resources

open access: yesEuropean Journal of Operational Research
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Berterottière, Lucas   +2 more
openaire   +3 more sources

Bench marking instances for flexible job shop scheduling problems and extended flexible job shop scheduling problems

open access: yes, 2012
For benchmarking purposes and to allow reproduction of the results for flexible job shop scheduling problems and extended flexible job shop scheduling problems, the sets of instances used are available for download at http://www.ime.usp.br/~cris/fjs ...
Anvari, B, Ochieng, WY, Angeloudis, P
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Application of job shop scheduling approach in green patient flow optimization using a hybrid swarm intelligence. [PDF]

open access: yes, 2022
With the increasing demand for hospital services amidst the COVID-19 pandemic, allocation of limited public resources and management of healthcare services are of paramount importance.
Chaussalet, Thierry J   +3 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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