Results 71 to 80 of about 66,379 (340)

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Development of a personalized visualization and analysis tool to improve clinical care in complex multisystem diseases with application to scleroderma

Arthritis Care &Research, Accepted Article.
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Constraint-based scheduling with total completion time criterion: models and applications [PDF]

, 2007
: Constraint programming (CP) offers flexible and effective tools for modeling combinatorial optimization problems. At the same time, scheduling with sum type optimization criteria, such as total completion time is challenging for CP.
Beck, J. Christopher, Kovács, András
core   +1 more source

Adaptive Genetic Algorithm Based on Individual Similarity to Solve Multi-Objective Flexible Job-Shop Scheduling Problem

IEEE Access, 2022
Aiming at the coupling of energy consumption and completion time in flexible job-shop scheduling, this paper took makespan and energy consumption as the optimization objectives, established a scheduling model, and proposed a scheduling strategy based on ...
Xu Liang, Yifan Liu, Xiaolin Gu, Ming Huang, Fajun Guo   +4 more
doaj   +1 more source

A Hybrid EA for Reactive Flexible Job-shop Scheduling

Procedia Computer Science, 2012
AbstractIn this paper, we consider a reactive flexible job-shop scheduling problem (rFJSP) under uncertainty environment. The most existing reactive scheduling methods are characterized by least commitment strategies such as real-time dispatching that create partial schedules based on local information.
Lin Lin, Mitsuo Gen, Katsuhisa Ohno, Yan Liang   +3 more
openaire   +2 more sources

The Integration of Process Planning and Shop Floor Scheduling in Small Batch Part Manufacturing [PDF]

, 1995
In this paper we explore possibilities to cut manufacturing leadtimes and to improve delivery performance in a small batch part manufacturing shop by integrating process planning and shop floor scheduling.
Kals, H.J.J., Zijm, W.H.M.
core   +2 more sources

Data‐Driven Distributed Safe Control Design for Multi‐Agent Systems

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents a data‐driven control barrier function (CBF) technique for ensuring safe control of multi‐agent systems (MASs) with uncertain linear dynamics. A data‐driven quadratic programming (QP) optimization is first developed for CBF‐based safe control of single‐agent systems using a nonlinear controller. This approach is then extended to the
Marjan Khaledi, Bahare Kiumarsi
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

3D‐Printed Architected Material for the Generation of Foam‐Based Protective Equipment

Advanced Engineering Materials, EarlyView.
This study investigates 3D‐printed architected structures as alternatives to traditional foams in protective gear. It focuses on customizing impact strength and damping through design and manufacturing integration. Testing shows these structures outperform conventional foams, offering enhanced customizability, lower weight, and tunable performance ...
Ali Zolfagharian, Gerard Bel Català, Daniel Saakes, Bernard Rolfe, Ian Gibson, Mehrshad Mehrpouya   +5 more
wiley   +1 more source