Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
Remote Sensing of Endogenous Pigmentation by Inducible Synthetic Circuits in Grasses
ABSTRACT Plant synthetic biology holds great promise for engineering plants to meet future demands. Genetic circuits are being designed, built and tested in plants to demonstrate the proof of concept. However, developing these components in monocots, which the world relies on for grain, lags behind dicot models, such as Arabidopsis thaliana and ...
Dong‐Yeon Lee +13 more
wiley +1 more source
Investigation on rub-impact response characteristics of gas generator rotor system under external excitation. [PDF]
Zhang H, Liu T, Zhao H, Wang Q.
europepmc +1 more source
Fully Tunable Phosphorylation of RPS6A Ensures the Successful Development of Arabidopsis Seedlings
ABSTRACT Light enhances protein translation, enabling young seedlings to rapidly and timely acquire photosynthetic capacities. Sequential phosphorylation of ribosomal protein S6 (RPS6) was implicated in the light‐enhanced translation; however, the exact phosphorylation sites and the biological relevance of RPS6 multi‐phosphorylation in seedling ...
Yueh Cho +2 more
wiley +1 more source
Physics-informed self-supervised diagnosis of rotating machinery using latent ODEs and transformer encoders. [PDF]
Amin MA +4 more
europepmc +1 more source
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary +5 more
wiley +1 more source
Optimization design and research of an interior double-radial asymmetric permanent magnet and salient-pole electromagnetic hybrid excitation generator for vehicles. [PDF]
Li C +5 more
europepmc +1 more source
Utilizing high‐throughput phenotyping to identify metribuzin tolerance in winter wheat
Abstract Plant breeders and weed scientists address weed management collaboratively by selecting for herbicide tolerance in breeding programs. Metribuzin, a Group 5 PSII‐inhibiting herbicide, is labeled for use in wheat (Triticum aestivum L.). However, application to currently available lines results in frequent, variable, and unpredictable crop injury.
Melinda Zubrod +4 more
wiley +1 more source
Study of the Equivalent Stiffness of a Non-Contact Piezoelectric Actuator's Micro-Displacement Amplification Mechanism. [PDF]
Li H +5 more
europepmc +1 more source
ABSTRACT Objectives This study compared the efficacy of Sonic (EDDY) and Er,Cr:YSGG (2780 nm) laser activation in eradicating Enterococcus faecalis biofilm formed in 3D‐printed molar replicas with two mesial canals and one distal canal. Materials and Methods An in vitro design was implemented using 20 3D‐printed mandibular molar replicas mimicking the ...
Margarida Macedo +4 more
wiley +1 more source

