Results 81 to 90 of about 1,923,601 (243)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Automatic application object migration in sensor networks [PDF]

, 2010
Object migration in wireless sensor networks has the potential to reduce energy consumption for a wireless sensor network mesh. Automated migration reduces the need for the programmer to perform manual static analysis to find an efficient layout solution.
McGregor, Anthony James, Hunkin, Paul
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Piezoelectric Sensing of Rigid-Flexible Coupled Free-Edge Rectangular Plates

International Journal of Aerospace Engineering
With the rapid development of space technology, rigid-flexible coupling systems are widely used in aerospace structures. Attitude-vibration coupling control requires a deep understanding of the rigid-flexible coupling dynamics of these systems.
Yudong Hu, Haoran Li
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A Flexible 32x32 SPAD Image Sensor with Integrated Microlenses

, 2015
The first single-photon avalanche diode (SPAD) image sensor fully integrated on flexible substrate is reported. The design consists of an array of 1024 quenched pixels with CMOS readout and addressing circuitries.
Sun, P., Ishihara, R. (author), Ishihara, R., Charbon, E. (author), Charbon, E., Sun, P. (author)   +5 more
core   +1 more source

Graphene Nanoplatelets/Polydimethylsiloxane Flexible Strain Sensor with Improved Sandwich Structure

In engineering measurements, metal foil strain gauges suffer from a limited range and low sensitivity, necessitating the development of flexible sensors to fill the gap.
Hongping Zhu, Ke Gao, Junshu Zhang, Shun Weng   +3 more
core   +1 more source

A Flexible PVDF Sensor for Forcecardiography

Sensors
Forcecardiography (FCG) uses force sensors to record the mechanical vibrations induced on the chest wall by cardiac and respiratory activities. FCG is usually performed via piezoelectric lead-zirconate titanate (PZT) sensors, which simultaneously record the very slow respiratory movements of the chest, the slow infrasonic vibrations due to emptying and
Salvatore Parlato, Jessica Centracchio, Eliana Cinotti, Gaetano D. Gargiulo, Daniele Esposito, Paolo Bifulco, Emilio Andreozzi   +6 more
openaire   +5 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source