Results 71 to 80 of about 120,965 (295)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Cost-Effective Fabrication of Transparent Strain Sensors via Micro-Scale 3D Printing and Imprinting

Nanomaterials, 2021
The development of strain sensors with high sensitivity and stretchability is essential for health monitoring, electronic skin, wearable devices, and human-computer interactions.
Rui Wang, Xiaoyang Zhu, Luanfa Sun, Shuai Shang, Hongke Li, Wensong Ge, Hongbo Lan   +6 more
doaj   +1 more source

Polymer-Based Self-Standing Flexible Strain Sensor

Journal of Sensors, 2010
The design and characterization of polymer-based self-standing flexible strain sensors are presented in this work. Properties as lightness and flexibility make them suitable for the measurement of strain in applications related with wearable electronics such as robotics or rehabilitation devices.
Fernando Martinez, Gregorio Obieta, Ion Uribe, Tomasz Sikora, Estibalitz Ochoteco   +4 more
openaire   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

Arthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

High Precision, Small Size and Flexible FBG Strain Sensor for Slope Model Monitoring

Sensors, 2019
In this paper, a soft fiber Bragg grating (FBG) strain sensor was constructed of a rubber strip, FBGs and steel plates, which exhibits the advantages of high precision and a small size.
Hongbin Xu, Xinyu Zheng, Weigang Zhao, Xu Sun, Feng Li, Yanliang Du, Bo Liu, Yang Gao   +7 more
doaj   +1 more source

3D printing highly stretchable conductors for flexible electronics with low signal hysteresis

Virtual and Physical Prototyping, 2022
Previous studies on UV-curable elastomer for digital light processing (DLP) 3D printing flexible electronics mostly focused on higher stretchability and healability, thereby ignoring rapid recoverability after a stretch which is very important for the ...
Jun Zhou, Honghao Yan, Chengyun Wang, Huaqiang Gong, Qiuxiao Nie, Yu Long   +5 more
doaj   +1 more source

Characterization of the modal parameters of composite laminates using innovative ultrathin polymer waveguide sensor foils [PDF]

, 2018
The use of composite materials, like glass- and carbon- fiber reinforced polymers, is expected to increase exponentially in the coming years. Consequently, in order to monitor the structural health of these materials, the development of new sensing ...
Lamberti, Alfredo, Missinne, Jeroen, Van Paepegem, Wim   +2 more
core   +2 more sources

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source