Results 41 to 50 of about 555,243 (314)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Numerical simulation to evaluate guidewire and catheter behavior during catheter introduction

open access: yesJournal of Biomechanical Science and Engineering, 2022
A national questionnaire survey on guidewire penetration accidents by the Japanese Society for Neuroendovascular Therapy reported examples of perforation accidents occurring “during catheter introduction” (75.2% of accidents). In this study, we evaluated
Kazuto TAKASHIMA   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Molecular competition induced Janus hydrogel bioelectronic interface for electroceutical modulation

open access: yesNature Communications
Janus hydrogel bioelectronic interfaces have long been challenged by complex fabrication procedures, poor controllability of asymmetric properties and weak interlayer bonding strength.
Xinyu Qu   +6 more
doaj   +1 more source

Structural characterization of projective flexibility

open access: yesDiscrete Mathematics, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Beifang Chen, Serge Lawrencenko
openaire   +1 more source

Flexible Models with Evolving Structure [PDF]

open access: yes, 2004
A type of flexible model in the form of a neural network (NN) with evolving structure is discussed in this study. We refer to models with amorphous structure as flexible models.
Angelov, Plamen, Filev, Dimitar
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Lubrication Performance of Misaligned Journal Bearings with Flexible Structure under Shock Load Conditions

open access: yesLubricants, 2023
Bearings might be damaged due to shock loads caused by disturbances, in addition to static loads. In this study, a flexible structure was applied to enhance the lubrication characteristics of misaligned journal bearings subjected to impact loads. When an
Sung-Ho Hong, Woo-Ju Jeon
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Application of Shape Memory Alloy Actuators to Vibration and Motion Control of Structural Systems: A Review

open access: yesApplied Sciences, 2023
This paper comprehensively reviews effective control applications using shape memory alloy (SMA) actuators. Among many applications, this paper focuses on the vibration and stiffness control of flexible structures and shape control in the aerospace ...
Jung Woo Sohn   +3 more
doaj   +1 more source

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