Results 141 to 150 of about 32,492 (266)

A Drive-Vibration Integrated Piezoelectric Actuator for Flexible Electrode Implantation. [PDF]

Micromachines (Basel)
Li X, Wu D, Lin X, Jiang T, Ma J, Li Y, Hu Y, Wang Y, Zhong H, Yang X, Li J, Wen J.   +11 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Splenic flexure colon cancer may represent a distinct prognostic subtype associated with elevated systemic inflammation and impaired nutritional status. [PDF]

Front Immunol
Yang ZH, Peng Y, Shang R, Tang XY, Zhou YW, Li XJ, Liao YC.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Synchronous Primary Adenocarcinomas of the Hepatic and Splenic Flexures Presenting as Acute Large Bowel Obstruction in a 38-Year-Old Man: A Case Report. [PDF]

Cureus
Gill J, Brady HW, Mbachi C.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Colonic perforation secondary to post endoscopic retrograde cholangio-pancreatography severe pancreatitis: a case report on the lethal potential of neglected cholelithiasis with review of literature. [PDF]

J Surg Case Rep
Anas M, Ali I, Jameel H, Purushottam S.
europepmc   +1 more source

Reticulate Hyperpigmentation of the Flexures

Actas Dermo-Sifiliográficas (English Edition), 2016
M, González-Olivares, L, Nájera, C, García-Donoso   +2 more
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Laparoscopic Repair of a Strangulated Right Diaphragmatic Hernia Following Blunt Trauma. [PDF]

Clin Case Rep
Aoun R, Akel R.
europepmc   +1 more source