Results 161 to 170 of about 53,981 (265)

Splenic flexure mobilization using a fusion surgery technique in robotic left hemicolectomy for colon cancer: a video vignette. [PDF]

Ann Coloproctol
Hashimoto M, Nishizawa Y, Kato S, Morimoto Y, Motoori M, Hata T, Fujitani K.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effects of 1 Gray radiation on the biophysical properties of the tibia and femur from hindlimb-suspended rats. [PDF]

Exp Physiol
Hill BJF, Mehta R.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

When colon cancer crosses boundaries: acute abdomen from direct pancreatic infiltration by a splenic flexure tumour. [PDF]

J Surg Case Rep
Sripathi S, Coleman AD, Krishnaraj AS, Pindicura S, Sharpe JP.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Submucosal colonic hemangioma at the splenic flexure mimicking a neoplastic lesion: a rare case report and diagnostic challenge. [PDF]

Int J Surg Case Rep
Dasuki M, Farhat H, Kanaan A, Dasuki A, Younan A.   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Flexural and Shear Performance of the Reinforced Beams made of Geopolymer Concrete: A review

Journal of Materials and Engineering Structures
Geopolymer is known to have many structural and nonstructural benefits, but the attractive characteristic of this novel material is that it depends essentially on a byproduct from different industries, and the use of Portland cement is absent.
Ashtar S. AL-LUHYBI, Taghreed Khaleefa MOHAMMED ALI, Azad A. MOHAMMED   +2 more
doaj  

Cholangitis, Choledocholithiasis and a Cholecystocolonic Fistula: A Case Report on a Rare Triple Surgical Challenge. [PDF]

Case Rep Surg
Jaffry K, Tran A, Bhowmik D, Crowe A, Naqash N.   +4 more
europepmc   +1 more source