Results 141 to 150 of about 173,287 (355)
Advanced Sustainable Systems, EarlyView.Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim
Verónica I. Dumit +43 more
wiley +1 more source
Development of a co-cured composite torque shaft for rudder of high speed aircraft [PDF]
, 2008 The Carbon Fibre reinforced Composites are widely used in developing various composite parts of civil and13; military aircraft due to its high specific strength and specific stiffness.
Dharmappa, BL +3 more
core +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Design and FEA Verification of Flexure Hinge for a Precision Platform
Jixie chuandong, 2017 The precision platform is a kind of high precision working platform which can provide the micrometer displacement. In precision platform design,flexible hinge structure is widely used as mechanism of transmission. The flexible hinge plays the key role in
Chang Xu +5 more
doaj
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Advanced Science, EarlyView.The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
wiley +1 more source
Design and Application of Series Flexure Mechanism based on Elliptical Flexure Hinge
Jixie chuandong, 2017 To increase the stroke of precision positioning system,a large stroke series flexure mechanism based on elliptical flexure hinge is presented.The method of pseudo-rigid-body model is applied to analyze the motion process of the series flexure mechanism ...
Shan Mingcai, Liu Shuang, Kong Xiangjie
doaj
ANNALS OF THE ORADEA UNIVERSITY. Fascicle of Management and Technological Engineering., 2013 Nicolae LOBONTIU +3 more
openaire +1 more source
Heuristically Adaptive Diffusion‐Model Evolutionary Strategy
Advanced Science, EarlyView.Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl +3 more
wiley +1 more source
Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis
Advanced Science, EarlyView.This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu +4 more
wiley +1 more source