Results 41 to 50 of about 60,701 (249)
Misalignments in an overconstrained flexure mechanism: A cross-hinge stiffness investigation [PDF]
, 2020 The exact-constraint design principle is commonly applied to flexure mechanisms to ensure deterministic behavior, but at the cost of reduced robustness, support stiffness, load capacity and usually an increased complexity of design.
Meijaard, J. P. +3 more
core +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Simulation to Compensate Ripple of Air Bearing Stage with Flexure Hinge Mechanisms
, 2011 This letter suggests a method to improve tracking performance of an H-type XY stage with air bearings and flexure hinge mechanisms. The flexure hinge mechanisms are employed to prevent failure of the air bearings when the yaw motion error of the H-type ...
Da Hoon Ahn +2 more
core +1 more source
Design optimization of a flexure spring used in small-sized ultra-precise optical instrument
Heliyon, 2023 Small-sized ultra-precise optical devices require compact compliant ortho-planar springs (COPS) aka. flexure springs, for precise, frictionless linear motion which depends highly on the design. A self-developed arm-hinge-linked design, named “Panto-style”
Jin Kim, Dong-Chan Lee, Ho-Sang Kim
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Jixie chuandong, 2017 The flexure hinge is the most basic compliant structure,the compliance is the most important performance parameter. The combined compliance method is proposed fully based upon the structure characteristic of the flexure hinge.
Guan Lixin, Liu Qingling
doaj
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Jixie chuandong, 2017 A flexure hinge positioning stage with giant magnetostrictive actuator（ GMA） as the driving unit is designed,which is composed of multi- group flexure hinges and guided by elastic deformation under force.
Mao Pengfei +3 more
doaj