Results 41 to 50 of about 147,191 (322)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Frontiers in Microbiology, 2022 Antimicrobial resistance (AMR) in bacteria in the livestock is a growing problem, partly due to inappropriate use of antimicrobial drugs. Antimicrobial use (AMU) occurs in Swedish dairy farming but is restricted to the treatment of sick animals based on ...
Rachel A. Hickman +8 more
doaj +1 more source
Coping with Space Neophobia in Drosophila melanogaster: The Asymmetric Dynamics of Crossing a Doorway to the Untrodden [PDF]
, 2015 Insects exhibit remarkable cognitive skills in the field and several cognitive abilities have been demonstrated in Drosophila in the laboratory. By devising an ethologically relevant experimental setup that also allows comparison of behavior across remote taxonomic groups we sought to reduce the gap between the field and the laboratory, and reveal as ...
arxiv +1 more source
Evaluation of daily residual pancreatic tumor motion for deep‐inspiration breath‐hold radiotherapy
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose Breath‐hold techniques are widely used in radiation therapy to minimize respiratory‐induced tumor or organ‐at‐risk motion. However, residual motion persists, necessitating a reliable daily evaluation method. Methods At our institution, fiducial markers serve as surrogates for target localization in pancreatic cancer treatment.
Weihua Mao +4 more
wiley +1 more source
Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue [PDF]
Molecular Systems Biology, 4:233:1-13, 2008, 2008 The fruit fly D. melanogaster is increasingly used as a model organism for studying acute hypoxia tolerance and for studying aging, but the interactions between these two factors are not well known. Here we show that hypoxia tolerance degrades with age in post-hypoxic recovery of whole-body movement, heart rate and ATP content.
arxiv +1 more source
Epidemiology and Infection, 1917 1. The chain of evidence incriminating the house fly as a disseminator of typhoid fever is at present fairly complete, but many of the links are weak and not thoroughly strengthened by experimentation.2. The bulk of experimental work has hitherto been done under highly unnatural and artificial circumstances and the results so obtained cannot be ...
openaire +3 more sources
Arthritis Care &Research, EarlyView.Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell +10 more
wiley +1 more source
Ecology and Evolution, 2021 The abandonment of historical land‐use forms within forests, such as grazing or coppicing, and atmospheric nitrogen deposition, has led to an increasing overgrowth of forest gaps and canopy closure in forest ecosystems of Central Europe.
Ralf Braun‐Reichert +2 more
doaj +1 more source