Results 121 to 130 of about 205,230 (331)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Evaluation of Reaction Forces on Rail-Supporting Points for Sleeper Floating Track System Using a Skin Sensor

Applied Sciences
Resilience pads provide elastic behavior and reduce impact and vibration loads in sleeper floating tracks, but their long-term degradation affects critical track components.
Jung-Youl Choi, Dae-Hui Ahn
doaj   +1 more source

Paranoia.Ada: Sample output reports [PDF]

Paranoia.Ada is a program to diagnose floating point arithmetic in the context of the Ada programming language. The program evaluates the quality of a floating point arithmetic implementation with respect to the proposed IEEE Standards P754 and P854 ...

core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

When Masking Multiplication Isn’t Enough: Exploiting Floating-Point Leakage in Falcon’s Pre-Image Computation

Transactions on Cryptographic Hardware and Embedded Systems
In this paper, we present an improved correlation power analysis (CPA) attack on the pre-image computation of the digital signature scheme Falcon. Our attack exploits new side-channel leakage that multiplication masking schemes fail to protect.
Keng-Yu Chen, Ming Qing Ching, Jiun-Peng Chen, Bo-Yin Yang   +3 more
doaj   +1 more source

A Model-Based Design Floating-Point Accumulator. Case of Study: FPGA Implementation of a Support Vector Machine Kernel Function. [PDF]

Sensors (Basel), 2020
Bassoli M, Bianchi V, De Munari I.
europepmc   +1 more source

cppdoubles: Fast Relative Comparisons of Floating Point Numbers in 'C++' [PDF]

, 2023
Nick Christofides
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source