Results 101 to 110 of about 4,958,187 (282)
Floating-floating point: a highly accurate number representation with flexible Counting ranges [PDF]
Efficient number representation is essential for federated learning, natural language processing, and network measurement solutions. Due to timing, area, and power constraints, such applications use narrow bit-width (e.g., 8-bit) number systems.
Cohen, Itamar, Einziger, Gil
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Floating-Point-Like Arithmetic for FPGA
, 2001 In recent years we have investigated the use of a logarithmic number representation as an alternative to floating-point. Efficient techniques have been developed to facilitate arithmetic comparable to single precision floating-point in the logarithmic ...
Matoušek, Rudolf
core
Floating Point to Fixed Point Conversion of C Code
, 1999 . In processors that do not support floating-point instructions, using fixed-point arithmetic instead of floating-point emulation trades off computation accuracy for execution speed. This trade-off is often profitable.
Andrea G.M. Cilio +4 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Numerical stability of DeepGOPlus inference.
PLoS ONEConvolutional neural networks (CNNs) are currently among the most widely-used deep neural network (DNN) architectures available and achieve state-of-the-art performance for many problems.
Inés Gonzalez Pepe +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A Compute-in-Memory Decoding Architecture for Posit-to-Floating-Point Conversion
IEEE AccessModern computing systems are increasingly adopting low-precision floating-point formats to reduce memory overhead, particularly in large-scale applications such as large language models and scientific computing.
Jae Hyung Ko +3 more
doaj +1 more source