Results 101 to 110 of about 4,709,241 (239)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Evaluation of Reaction Forces on Rail-Supporting Points for Sleeper Floating Track System Using a Skin Sensor

open access: yesApplied Sciences
Resilience pads provide elastic behavior and reduce impact and vibration loads in sleeper floating tracks, but their long-term degradation affects critical track components.
Jung-Youl Choi, Dae-Hui Ahn
doaj   +1 more source

Fear of floating [PDF]

open access: yes
Many emerging market countries have suffered financial crises. One view blames soft pegs for these crises. Adherents to that view suggest that countries move to corner solutions--hard pegs or floating exchange rates.
Calvo, Guillermo, Reinhart, Carmen
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

When Masking Multiplication Isn’t Enough: Exploiting Floating-Point Leakage in Falcon’s Pre-Image Computation

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
In this paper, we present an improved correlation power analysis (CPA) attack on the pre-image computation of the digital signature scheme Falcon. Our attack exploits new side-channel leakage that multiplication masking schemes fail to protect.
Keng-Yu Chen   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Secret Key Recovery of FALCON using Simple Power Analysis in Conditional Calculator

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
Among the NIST-standardized algorithms, FALCON is a lattice-based digital signature scheme that offers strong security and compactness. However, FALCON’s reliance on floating-point arithmetic makes it vulnerable to side-channel attacks.
GyuSang Kim   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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