Results 81 to 90 of about 97,714 (259)

Enhancing CuFP Library with Self-Alignment Technique

open access: yesComputers
High-Level Synthesis (HLS) tools have transformed FPGA development by streamlining digital design and enhancing efficiency. Meanwhile, advancements in semiconductor technology now support the integration of hundreds of floating-point units on a single ...
Fahimeh Hajizadeh   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Floating point representations in quantum circuit synthesis

open access: yesNew Journal of Physics, 2013
We provide a non-deterministic quantum protocol that approximates the single qubit rotations R _x (2 ϕ ^2 _1 ϕ ^2 _2 ) using R _x (2 ϕ _1 ) and R _x (2 ϕ _2 ) and a constant number of Clifford and T operations.
Nathan Wiebe, Vadym Kliuchnikov
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Lightweight Floating-Point Arithmetic: Case Study of Inverse Discrete Cosine Transform

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
To enable floating-point (FP) signal processing applications in low-power mobile devices, we propose lightweight floating-point arithmetic. It offers a wider range of precision/power/speed/area trade-offs, but is wrapped in forms that hide the ...
Fang Fang, Chen Tsuhan, Rutenbar Rob A
doaj   +1 more source

Study of FPGA-based Error-controllable Floating-point Operation Accelerators [PDF]

open access: yesJisuanji gongcheng
Floating-point operations are fundamental operations in the field of High-Performance Computing(HPC). In the context of big data and cloud computing,the amount of data that HPC platforms need to process is continuously growing,and the round-off error of ...
GUAN Mingxiao, LIU Jiakun, ZHANG Hongrui, HE Anping
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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