Results 61 to 70 of about 97,714 (259)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Floating-point profiling of ACTS using Verrou [PDF]

EPJ Web of Conferences, 2019
Floating-point computations play a central role in scientific computing. Achieving high numerical stability in these computations affects not just correctness, but also computing efficiency, by accelerating the convergence of iterative methods and ...
Grasland Hadrien, Févotte François, Lathuilière Bruno, Chamont David   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hammering Floating-Point Arithmetic

, 2023
AbstractSledgehammer, a component of the interactive proof assistant Isabelle/HOL, aims to increase proof automation by automatically discharging proof goals with the help of external provers. Among these provers are a group of satisfiability modulo theories (SMT) solvers with support for the SMT-LIB input language.
Olle Torstensson, Tjark Weber
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Tunable Floating-Point Adder [PDF]

IEEE Transactions on Computers, 2019
In this work, we address the design of an adder in Tunable Floating-Point (TFP) precision. TFP is a variable precision format in which a given precision can be chosen for a single operation by selecting a specific number of bits for significand and exponent in the floating-point representation.
openaire   +2 more sources

Performance Analysis of a Floating Wind–Wave Power Generation Platform Based on the Frequency Domain Model

Journal of Marine Science and Engineering
Integrating wave energy converters (WECs) onto floating offshore wind turbine platforms has emerged as a recent focal point of research aiming to achieve synergistic marine energy utilization and enhance the spatial efficiency of renewable energy.
Mingsheng Chen, Jiang Deng, Yi Yang, Hao Zhou, Tao Tao, Shi Liu, Liang Sun, Lin Hua   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source