Results 61 to 70 of about 205,230 (331)
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim +8 more
wiley +1 more source
Interval Slopes as Numerical Abstract Domain for Floating-Point Variables
The design of embedded control systems is mainly done with model-based tools such as Matlab/Simulink. Numerical simulation is the central technique of development and verification of such tools.
A. Chapoutot +29 more
core +3 more sources
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source
Multiple-Input Floating-Point Adders: A Comprehensive Review
Floating-point addition is pivotal in various computational applications, including scientific computing, machine learning, and graphics processing. Traditional two-input floating-point adders (FPADD2) are widely used but become bottlenecks in scenarios ...
Sami Ul Haq +2 more
doaj +1 more source
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Enabling Bitwise Reproducibility for the Unstructured Computational Motif
In this paper we identify the causes of numerical non-reproducibility in the unstructured mesh computational motif, a class of algorithms commonly used for the solution of PDEs.
Bálint Siklósi +2 more
doaj +1 more source
Floating-point profiling of ACTS using Verrou [PDF]
Floating-point computations play a central role in scientific computing. Achieving high numerical stability in these computations affects not just correctness, but also computing efficiency, by accelerating the convergence of iterative methods and ...
Grasland Hadrien +3 more
doaj +1 more source
Geometric Rounding and Feature Separation in Meshes
Geometric rounding of a mesh is the task of approximating its vertex coordinates by floating point numbers while preserving mesh structure. Geometric rounding allows algorithms of computational geometry to interface with numerical algorithms.
Milenkovic, Victor, Sacks, Elisha
core +1 more source

