Results 41 to 50 of about 4,958,187 (282)
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Optimizing FDTD Memory Bandwidth by Using Block Float-Point Arithmetic
Finite-difference time-domain is a numerical method used for modelling of computational electrodynamics. The method is resource intensive, especially regarding memory usage. Multiple memory accesses are required per single computation so memory bandwidth
Stefan Pijetlovic +2 more
doaj +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Numerical Difficulties in Pre-University Informatics Education and Competitions
It is easy to underestimate the difficulties of using floating-point numbers in programming. This is especially the case in pre-university informatics education and competitions, where one is often led to believe that floating-point arithmetic is a good ...
Gyula HORVÁTH, Tom VERHOEFF
doaj +1 more source
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
A Hybrid Method for Optimization Modulo Theory of Floating-Point Numbers
Optimization Modulo Theory (OMT) is an important extension of Satisfiability Modulo Theory (SMT), aiming to find models that satisfy constraints while optimizing objective functions. OMT naturally arises in program analysis and formal methods, making OMT
Xu Yang +4 more
doaj +1 more source
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
High-Performance Multi-Precision Tool for Floating-Point Computations [PDF]
This paper presents a MATLAB toolbox for multiple-precision arithmetic, enabling high-precision numerical computations beyond the standard double-precision format. The development step and functionality of the toolbox are described, and how it integrates
L. Leitold, M. Alrwashdeh, Z. Kollar
doaj
An Asynchronous Floating-Point Multiplier [PDF]
We present the details of our energy-efficient asynchronous floating-point multiplier (FPM). We discuss design trade-offs of various multiplier implementations. A higher radix array multiplier design with operand-dependent carry-propagation adder and low handshake overhead pipeline design is presented, which yields significant energy savings while ...
Basit Riaz Sheikh, Rajit Manohar
openaire +1 more source

