Results 191 to 200 of about 97,714 (259)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The dual effects of social capital on mental health: a study of structural and cognitive dimensions among the floating older adults in China. [PDF]

Front Public Health
Huang J, Luo Z, Yao S.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

High-Resolution dataset on elderly care facility accessibility and inequality in 21 Chinese cities (2020). [PDF]

Sci Data
Han X, Wang Y, Wei Z, Jiang H.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Lightweight Real-Time Navigation for Autonomous Driving Using TinyML and Few-Shot Learning. [PDF]

Sensors (Basel)
Ali W, Iqbal A, Wadood A, Park H, Kang BO.   +4 more
europepmc   +1 more source

Point-to-Point Macular Structure-Function Relationships in Healthy and Glaucomatous Eyes Using OCT and Microperimetry. [PDF]

J Clin Med
Garcia-Medina JJ, Sobrado-Calvo P, Lopez-Canovas L, Lopez-Bernal MD, Pinazo-Duran MD, Zanon-Moreno V, Del-Rio-Vellosillo M.   +6 more
europepmc   +1 more source

Dopamine-Mediated Attenuation of OECT-Based Aqueous Artificial Chemical Synapses. [PDF]

ACS Appl Mater Interfaces
Zhang H, Xu X, He W, Isobe A, Liu Y, Zhao Y, Michinobu T.   +6 more
europepmc   +1 more source

Medication Samples and Smoking Cessation Among Adults: A Randomized Clinical Trial.

JAMA Netw Open
Carpenter MJ, Smith TT, Wahlquist AE, Toll BA, Cropsey KL, Ware EC, Kaczmar JM, Dahne J, Gray KM.   +8 more
europepmc   +1 more source