Results 221 to 230 of about 7,246 (295)

Medical Reasoning With Large Language Models: A Systematic Review and Evaluation

open access: yesiNew Medicine, EarlyView.
ABSTRACT Large language models (LLMs) have achieved strong performance on medical exam–style tasks, motivating growing interest in their deployment in real‐world clinical settings. However, clinical decision‐making is inherently safety‐critical, context‐dependent, and conducted under evolving evidence.
Xiaohan Ren   +6 more
wiley   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang   +5 more
wiley   +1 more source

Role of Depression and Anxiety in Eating Disorder Symptomatology in Higher Levels of Care for Girls With Anorexia Nervosa

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Although the prevalence of affective comorbidities with eating disorders (ED) has been well established, the three‐way relation between ED, depression, and anxiety symptoms has not been explored in an intensive adolescent treatment setting.
Jasmine Ghannadpour   +3 more
wiley   +1 more source

Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Environmental pressures shape survival and life‐history dynamics partly by triggering the release of glucocorticoids, whose short‐term benefits but long‐term costs make it essential to understand what drives their levels. Here, we used an experimental manipulation of two environmental stressors—food availability and parasite burden—to directly
Sarah E. Wolf   +4 more
wiley   +1 more source

Improving nutritional assessment in pediatric anorexia nervosa: Clinical value of key serum biomarkers

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Reliable biochemical markers of starvation are needed to improve detection and monitoring of starvation in pediatric anorexia nervosa (AN), thus we explored new and revisited old potential serum biochemical markers. Methods In this prospective cohort study we included 65 pediatric patients with AN.
Ante Vidović   +8 more
wiley   +1 more source

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