Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Paratuberculosis in small ruminants in the Sudan: prevalence and risk factors. [PDF]
Idris SM+12 more
europepmc +1 more source
Heritability estimates of body weight and growth rate in a flocks of Ossimi Sheep [PDF]
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Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Risk factors for highly pathogenic avian influenza outbreaks in Japan during 2022-2023 season identified by additive Bayesian network modeling. [PDF]
Yamaguchi E+3 more
europepmc +1 more source
A survey of mortality in three adult broiler breeder flocks [PDF]
Helen G.R. Jones+2 more
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Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Farmer field schools as interventions to reduce the need for antimicrobials in agrifood systems: a longitudinal analysis of layer farmer field school graduates and non-graduates in Kenya. [PDF]
Caudell MA+7 more
europepmc +1 more source
Autumn flocking Habits of the Red-winged Blackbird in Southern Manitoba
Lawrie B. Smith, Ralph D. Bird
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