FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Non-IID and aware federated intrusion detection with PBFT with secured model aggregation for multi institutional healthcare internet of things networks. [PDF]
Sci RepSengan S, Shieh CS.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Seroprevalence of <i>Toxoplasma gondii</i> infection and risk factors in sheep from Afyonkarahisar province, Türkiye. [PDF]
Front Vet SciTunç AC +4 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics. [PDF]
EcologyPérez-Umphrey AA +6 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Prevalence and associated risk factors of selected breast muscle myopathies in broiler flocks of northern Iran. [PDF]
Poult SciAtef A, Mosleh N, Lari MA.
europepmc +1 more source
, 2012 Source: Paul Heyse: Gesammelte Werke, 3 Reihen in 15 Bänden, Stuttgart: Cotta, 1924. [Nachdruck: Hildesheim, Zürich, New York: Georg Olms Verlag, 1991].
openaire +1 more source