Results 91 to 100 of about 247,347 (299)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Lowering the floor of the SF-6D Utility function: an application using Spanish data [PDF]

, 2010
© 2010 Los autores. © 2010 Fundación BBVA. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Submitted version of a Published Work that appeared in final ...
Méndez Martínez, Ildefonso, Abellán Perpiñán, José María, Sánchez Martínez, Fernando Ignacio, Martínez Pérez, Jorge Eduardo   +3 more
core  

The pelvic floor puzzle in the spotlight:the association between pelvic floor muscle function and pelvic floor symptoms in men and women [PDF]

Pelvic floor symptoms such as lower urinary tract symptoms, defecation problems, sexual dysfunction and pelvic pain are prevalent in men en women. However, the relation between pelvic floor (dys)function and pelvic floor symptoms is unclear.
Notenboom-Nas, Françoise
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Pulmonary function and high-resolution computed tomography examinations among offshore drill floor workers [PDF]

, 2017
Purpose: The aim of this study was to assess short-term changes in pulmonary function in drill floor workers currently exposed to airborne contaminants generated as a result of drilling offshore.
Ellingsen, Dag, Raymond Olsen, Anne Günther, Trond Mogens Aaløkken, Bente Ulvestad, Skare, Øivind, Yngvar Thomassen, Kirkhus, Niels Einar, Günther, Anne, Ulvestad, Bente, Niels E. Kirkhus, Olsen, Raymond, May Brit Lund, Dag G. Ellingsen, Thomassen, Yngvar, Aaløkken, Trond Mogens, Samersaw-Lund, May Brit, Øivind Skare   +17 more
core   +1 more source

CHANGES OF PELVIC FLOOR MUSCLE FUNCTION DURING PREGNANCY

Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2019
Objective: It is known, that incontinence rarely develops during pregnancy. The authors examined pelvic floor muscle function changes during pregnancy.
Márta HOCK, Péter TARDI, Eszter AMBRUS, Anett TÓVÁRI, Brigitta HAJNAL, Brigitta SZILÁGYI, Eleonora LEIDECKER, Bálint MOLICS, Melinda JÁROMI, János KRÁNICZ, József BÓDIS, Pongrác ÁCS   +11 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Pelvic Floor Muscle Training vs. Vaginal Vibration Cone Therapy for Postpartum Dyspareunia and Vaginal Laxity

Medicina
Background and Objectives: Pelvic floor dysfunction and sexual health issues are common postpartum due to weakened pelvic muscles, significantly impacting women’s quality of life (QoL).
Federico Villani, Izabella Petre, Florina Buleu, Stela Iurciuc, Luciana Marc, Adrian Apostol, Chiara Valentini, Elisabetta Donati, Tommaso Simoncini, Ion Petre, Cristian Furau   +10 more
doaj   +1 more source