Results 81 to 90 of about 247,347 (299)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Pelvic floor function is independently associated with pelvic organ prolapse [PDF]

, 2009
To investigate the risk factors for pelvic organ prolapse (POP), including physical activity, clinically measured joint mobility and pelvic floor muscle (PFM ...
Braekken, I H, Bø, K, Ellström-Engh, Marie,, Holme, I M, Majida, M   +4 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

ZEROS OF THE DEGREE 2 FLOOR FUNCTION [PDF]

Neste trabalho, estamos interessados em estudar funções lineares e quadráticas envolvendo a função piso, as quais denominamos funções piso de graus 1 e 2, respectivamente.
Costa, Eudes, Carvalho, Fernando, Mesquita, Élis Gardel   +2 more
core   +1 more source

Pelvic floor muscle strength and sexual function in women [PDF]

, 2015
Introduction : Pelvic floor (PF) muscles react to sexual stimuli with increased local blood circulation and involuntary contractions during orgasm. The training of the PF musculature helps in the improvement of the female sexual function. Objective : To
Ana Paula Kruger, Fernando Luiz Cardoso, Cinara Sacomori, Janeisa Franck Virtuoso   +3 more
core   +3 more sources

Female Sexual Function and Quality of Life After Pelvic Floor Surgery

Obgynia
Introduction: Pelvic floor surgery can significantly affect female sexual function and quality of life, impacting clinical outcomes and patient satisfaction. Understanding these effects is crucial for optimizing patient care.
Ratih Krisna, Amir Fauzi, Murwani Emasrissa Latifah, Hana Andrina, Putri Arini, I Gede Agus Astawa, Bella Stevanny   +6 more
doaj   +1 more source

A Note on the Integration of Floor Functions

, 2023
In 1994, Steven W. Sy \cite{1} evaluated an indefinite integral of $[x]$ ($= \lfloor x \rfloor$) using an area argument and the fundamental theorem of calculus. In this note, we evaluate the indefinite integral of floor functions using a similar approach by Steven W. Sy.
openaire   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Pelvic floor exercises for erectile dysfunction [PDF]

, 2005
OBJECTIVE: To examine the role of pelvic floor exercises as a way of restoring erectile function in men with erectile dysfunction. PATIENTS AND METHODS: In all, 55 men aged >20 years who had experienced erectile dysfunction for ≥6 months were recruited ...
Swinkels, Annette, Speakman, Mark J., Dunn, Christopher D.R., Feneley, Roger C.L., Dorey, Grace   +4 more
core   +1 more source

Female Sexual Dysfunction and Related Quality Of Life: Impact of Pelvic Floor Muscle Training [PDF]

Egyptian Journal of Health Care
Background: Female sexual dysfunction is a real worldwide health problem during their reproductive period, often undiagnosed and untreated in women and are associated with decreased quality of life.
Eman Ali Abd El Moaty Sheha, Ola Hussein Abo ElMaaty Mohamed, Walaa Khalaf Gooda, Hanan Elzeblawy Hassan   +3 more
doaj   +1 more source