Results 61 to 70 of about 247,347 (299)
Quantitative tools to assess pelvic floor muscle function — systematic review [PDF]
Objectives: Urinary incontinence is pelvic floor muscles dysfunction, most often caused by a weakening of their strength. There are no guidelines on how to evaluate pelvic floor muscle function.
Michalik, Dominika; Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Cracow, Poland; PelviFly, Warsaw, Poland +2 more
core +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Journal of Physical Fitness and Sports MedicineStrengthening of the hip external rotator muscles may improve pelvic floor muscle function. In this study, we examined the relationship between hip external rotator strength and pelvic floor muscle function in nulliparous women.
Satoko Nakano +4 more
doaj +1 more source
Functional anatomy of pelvic floor
Archivio Italiano di Urologia e Andrologia, 2016 Generally, descriptions of the pelvic floor are discordant, since its complex structures and the complexity of pathological disorders of such structures; commonly the descriptions are sectorial, concerning muscles, fascial developments, ligaments and so on. On the contrary to understand completely nature and function of the pelvic floor it is necessary
openaire +4 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Association between preterm labour and pelvic floor muscle function [PDF]
, 2018 We hypothesised that the pressure on the cervix increases with advancing gestation and it may lead to a cervical shortening and cause preterm labour in women with weak pelvic floor muscles. The aim of this prospective study was to measure vaginal resting
Hasan Bozkaya +3 more
core +1 more source
Prime Floor and Prime Ceiling Functions
, 2022 See the abstract in the attached pdf.
openaire +2 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Determining the Sufficiency of the bHLH Gene Nato3 in Dopamine Neurogenesis [PDF]
, 2012 Floor plate cells of the mesencephalon have the ability to become more floor plate cells or differentiate into dopamine containing neurons. Maturation of these neurons can be marked by the stage of differentiation. When dopamine neurons of the substantia
Kaufman, Darcy Nichole
core +1 more source