Results 61 to 70 of about 1,210,302 (292)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Pelvic floor and abdominal muscle cocontraction in women with and without pelvic floor dysfunction: a systematic review and meta-analysis [PDF]

Clinics
There is an ongoing discussion regarding abdominal muscle (AbM) and pelvic floor muscle (PFM) synergism. Therefore, this study aimed to investigate the cocontraction between AbMs and PFMs in women with or without pelvic floor dysfunction (PFD).
Giovana Vesentini, Regina El Dib, Leonardo Augusto Rachele Righesso, Fernanda Piculo, Gabriela Marini, Guilherme Augusto Rago Ferraz, Iracema de Mattos Paranhos Calderon, Angélica Mércia Pascon Barbosa, Marilza Vieira Cunha Rudge   +8 more
doaj   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Investigating the Impact of Benign Indication Hysterectomy on Pelvic Floor Symptoms and Sexual Function: A Prospective Study Integrating Pelvic Floor Ultrasonography and Surface Electromyography Test

Women's Health Reports
Objective: This prospective study aimed to investigate the short-term effects of single-port laparoscopic hysterectomy for benign conditions on postoperative pelvic floor symptoms, pelvic floor structure, and pelvic floor muscle function.
Wanwen Chen, Kai Chen, Yan Wang, Yang Shen   +3 more
doaj   +1 more source

Averaged kernel floor localization algorithm for multi-floor WLAN positioning [PDF]

, 2017
Multi-floor positioning is important especially to locate a user correctly in an urban area where multi-level buildings are located. In two-stage (vertical and horizontal) positioning, floor level is first determined prior to horizontal localization ...
Abbas, Zulkifly, Abd Rahman, Mohd Amiruddin   +1 more
core  

Consequences of cosmic microwave background-regulated star formation

, 2010
It has been hypothesized that the cosmic microwave background (CMB) provides a temperature floor for collapsing protostars that can regulate the process of star formation and result in a top-heavy initial mass function at high metallicity and high ...
Bailin, Dahlén, Dotter, Greg Stinson, Haardt, Harris, Hinshaw, Hugh Couchman, James Wadsley, Jappsen, Jeremy Bailin, Kennicutt, Klypin, Kroupa, Lilly, Madau, Marín-Franch, Omukai, Ortolani, Raiteri, Sarajedini, Shen, Sijing Shen, Smith, Smith, Spergel, Stinson, Thielemann, Widrow, William E. Harris   +29 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Primal Recovery from Consensus-Based Dual Decomposition for Distributed Convex Optimization [PDF]

, 2015
Dual decomposition has been successfully employed in a variety of distributed convex optimization problems solved by a network of computing and communicating nodes.
Jamali-Rad, Hadi, Simonetto, Andrea
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Female Sexual Function and Quality of Life After Pelvic Floor Surgery

Obgynia
Introduction: Pelvic floor surgery can significantly affect female sexual function and quality of life, impacting clinical outcomes and patient satisfaction. Understanding these effects is crucial for optimizing patient care.
Ratih Krisna, Amir Fauzi, Murwani Emasrissa Latifah, Hana Andrina, Putri Arini, I Gede Agus Astawa, Bella Stevanny   +6 more
doaj   +1 more source