Results 41 to 50 of about 1,210,302 (292)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population [PDF]

, 2019
Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity.
Calfee, Ryan P, Cipriano, Cara A, Dalton, Jay F, McDonald, Douglas J, O\u27Keefe, Regis J, Ploetze, Kristen L   +5 more
core   +1 more source

The Impact of cold gas accretion above a mass floor on galaxy scaling relations

, 2010
Using the cosmological baryonic accretion rate and normal star formation efficiencies, we present a very simple model for star-forming galaxies (SFGs) that accounts for the mass and redshift dependencies of the SFR-Mass and Tully-Fisher relations from z ...
A. Dekel, Barkana, Bauermeister, Bell, Blitz, Bouché, Bouché, Bournaud, Burkert, Cantalupo, Cattaneo, Choi, Cresci, Daddi, Daddi, Daddi, Daddi, Daddi, Dahlen, Damen, Damen, Dekel, Dijkstra, Drory, Dutton, Elmegreen, Elmegreen, Erb, Erb, Erb, Finlator, Förster Schreiber, Förster Schreiber, G. Cresci, Genel, Genel, Genzel, Genzel, Giovanelli, Gnedin, Gonzalez, Heckman, Hopkins, Hopkins, Jimenez, K. L. Shapiro, Kassin, Krumholz, L. Tacconi, Larson, Law, Law, Lilly, Madau, Martin, Martin, McGaugh, Mobasher, Moster, Murray, N. Bouché, N. M. Förster Schreiber, Nagamine, Navarro, Noeske, Noeske, Ocvirk, Oesch, Pannella, Pawlik, Pieri, Quinn, R. Genzel, R. I. Davies, Rosenberg, Rupke, S. Genel, Sawicki, Schiminovich, Shankar, Shapiro, Shapiro, Shapley, Stark, Stewart, Thomas, Thomas, Tully, Tully, Wechsler, Wong, Wright, Yabe, Zwaan   +93 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The Integral Theory, Pelvic Floor Biomechanics, and Binary Innervation [PDF]

International Neurourology Journal
The pelvic floor biomechanics and sphincter functioning are essential for understanding pelvic floor dysfunction and the pathophysiology of the pelvic organs. The pelvic floor consists of muscles, fascial connections and ligaments.
Jörgen Quaghebeur, Peter Petros, Jean-Jacques Wyndaele, Stefan De Wachter   +3 more
doaj   +1 more source

Digestive and locomotor capacity show opposing responses to changing food availability in an ambush predatory fish [PDF]

, 2018
Metabolic rates vary widely within species, but little is known about how variation in the “floor” (i.e. standard metabolic rate in ectotherms; SMR) and “ceiling” (maximum metabolic rate; MMR) for an individual's aerobic scope (AS) are linked with the ...
Ali, Auer, Auer, Bartoń, Bates, Bell, Biro, Biro, Boos, Brett, Burton, Careau, Careau, Careau, Chabot, Claireaux, Clark, Fisher, Fry, Fu, Fu, Fu, Halsey, Hervant, Hopkins, Jain, Kern, Killen, Killen, Killen, Killen, Killen, Killen, Killen, Killen, Killen, Lande, Lee, Marras, Marras, Martínez, Martínez, McCue, Metcalfe, Millidine, Méndez, Nakagawa, Nakagawa, Nelson, Nicieza, Norin, Norin, Norin, Norin, Norin, O'Connor, Pang, Post, Rosenfeld, Royle, Secor, Van Leeuwen, Wang, Xie, Yan, Yang, Zeng, Álvarez   +67 more
core   +1 more source

Functional anatomy of pelvic floor

Archivio Italiano di Urologia e Andrologia, 2016
Generally, descriptions of the pelvic floor are discordant, since its complex structures and the complexity of pathological disorders of such structures; commonly the descriptions are sectorial, concerning muscles, fascial developments, ligaments and so on. On the contrary to understand completely nature and function of the pelvic floor it is necessary
openaire   +4 more sources

Curious Bounds for Floor Function Sums

, 2017
19 ...
Thanatipanonda, Thotsaporn, Wong, Elaine
openaire   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Uncovering changes in proteomic signature of rat pelvic floor muscles in pregnancy. [PDF]

, 2019
BackgroundStructural and functional changes of the rat pelvic floor muscles during pregnancy, specifically, sarcomerogenesis, increase in extracellular matrix content, and higher passive tension at larger strains protect the integral muscle components ...
Alperin, Marianna, Boscolo, Francesca Sesillo, Burnett, Lindsey A, Laurent, Louise C, Wong, Michelle   +4 more
core   +1 more source