Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source
A New Penetration Depth Method Using Proctor Compaction Test for Determining the Optimal Starting Time of Hardening Topping in Concrete Flooring. [PDF]
Michalik A, Zychowicz J.
europepmc +1 more source
Reconfigurable Selector‐Only Memory (SOM) for Scalable Neuromorphic Computing
ABSTRACT Highly scalable reconfigurable neuromorphic devices are critical for addressing continual‐learning challenges in artificial intelligence. However, the scalability of existing reconfigurable devices is severely constrained by limited operating margins and insufficient process maturity.
Jin‐Yu Wen +7 more
wiley +1 more source
Emissions of DEHP-free PVC flooring. [PDF]
Castagnoli E +9 more
europepmc +1 more source
Gait Analysis in Walking and Trotting Dairy Cows on Different Flooring Types with Novel Mobile Pressure Sensors and Inertial Sensors. [PDF]
Fischer D +5 more
europepmc +1 more source
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Increasing the Recycling of PVC Flooring Requires Phthalate Removal for Ensuring Consumers' Safety: A Cross-Checked Substance Flow Analysis of Plasticizers for Switzerland. [PDF]
Klotz M +5 more
europepmc +1 more source
Mixed‐Polymer Hole Transport Layers Reinforce Au‐Anode Top Emitting Perovskite Light Emitting Diodes
Au‐anode corrosion is shown to occur rapidly under voltage bias in MAPbI3 perovskite LEDs. Resulting Au+ migration quickly leads to device shorting and unstable emission during constant current driving. We demonstrate that using a simple mixed‐polymer hole transport layer containing polyTPD and PVK can reduce Au‐corrosion and stabilize LED operation ...
James C. Loy +5 more
wiley +1 more source
Heritage Decorative Wooden Flooring Restoration-Systemotechnical Approach and Risk Analysis. [PDF]
Juszczyk M +4 more
europepmc +1 more source
A Brief Evaluation of Antioxidants, Antistatics, and Plasticizers Additives from Natural Sources for Polymers Formulation. [PDF]
Almeida S +7 more
europepmc +1 more source

