Results 181 to 190 of about 150,641 (326)

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten   +15 more
wiley   +1 more source

Study on Bacterial Flora of Burn Wound Infection: A Need for Microbiological Surveillance in Burn Units [PDF]

open access: diamond, 2017
T. Sabetha   +4 more
openalex   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert   +5 more
wiley   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

open access: yesFood Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang   +7 more
wiley   +1 more source

Best microbiological practice recommendations for the diagnosis of peri-prosthetic joint infections: the CRIOGO bacteriology reference center network. [PDF]

open access: yesAnn Clin Microbiol Antimicrob
Bémer P   +12 more
europepmc   +1 more source

Accelerating Enzyme Engineering With Artificial Intelligence in Biocatalysis: Challenges and Opportunities

open access: yesFood Bioengineering, EarlyView.
ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu   +11 more
wiley   +1 more source

Microbial profile and putative microbial origin of anorectal abscess based on 16S rDNA sequencing. [PDF]

open access: yesFront Cell Infect Microbiol
Chen S   +7 more
europepmc   +1 more source

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