Results 101 to 110 of about 882,248 (296)
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini +19 more
wiley +1 more source
Subdifferential Test for Optimality
We provide a first-order necessary and sufficient condition for optimality of lower semicontinuous functions on Banach spaces using the concept of subdifferential.
Jules, Florence, Lassonde, Marc
core +3 more sources
Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral +41 more
wiley +1 more source
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Agglomerative Magnets and Informal Regulatory Networks: Electricity Market Design Convergence in the USA and Continental Europe [PDF]
The absence of one broadly accepted design template for liberalised electricity markets induces regulatory competition and institutional diversity. Focussing on continental Europe and the USA, this analysis explores how agents and structures accelerate ...
Jens Weinmann
core
Diffractive exclusive production of heavy quark pairs at high energy proton-proton collisions
We discuss exclusive double diffractive (EDD) production of heavy quark - heavy antiquark pairs at high energies. Differential distributions for $c \bar c$ at $\sqrt{s}$ = 1.96 GeV and for $b \bar b$ at $\sqrt{s}$ = 14 TeV are shown and discussed ...
Maciula, Rafal +2 more
core +1 more source
CTP Ontology: A Semantic Model for Structuring Cultural Thematic Paths
Abstract A thematic path enhances the appreciation of cultural heritage by connecting diverse cultural objects through shared themes. This study introduces the Cultural Thematic Path (CTP) Ontology, designed to support the creation, organization, description, publication, and management of thematic paths within the GLAM (Galleries, Libraries, Archives,
Tiziana Pasciuto +2 more
wiley +1 more source
Il Gonfaloniere di Giustizia e le banche: un conflitto d’interessi nella Firenze medievale
This short paper outlines how the Florentine office of Gonfaloniere di Giustizia—created in 1293 to guarantee judicial independence—was repeatedly held by leading bankers between the fourteenth and fifteenth centuries.
Marco Saba
doaj +1 more source
\u27La Maggior Porcheria Del Mondo\u27: Documents for Ammannati\u27s Neptune Fountain
The story of the creation of the Neptune Fountain on the Piazza della Signoria in Florence is long and tortuous. Scholars have drawn on a wealth of documentary material regarding the competition for the commission, the various phases of the fountain\u27s
Else, Felicia M.
core

