Results 81 to 90 of about 105,686 (259)

Il Gonfaloniere di Giustizia e le banche: un conflitto d’interessi nella Firenze medievale

open access: yesNordicum-Mediterraneum
This short paper outlines how the Florentine office of Gonfaloniere di Giustizia—created in 1293 to guarantee judicial independence—was repeatedly held by leading bankers between the fourteenth and fifteenth centuries.
Marco Saba
doaj   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini   +19 more
wiley   +1 more source

Effective Performance of the 2022 American College of Rheumatology/EULAR Classification Criteria for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in Pediatric Patients: An ARChiVe Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral   +41 more
wiley   +1 more source

The human foundations of anatomy at The University of Sydney: One hundred and one years of body procurement

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Body procurement at The University of Sydney has a long history. Anatomy legislation (1881 Anatomy Act) modeled on the British Anatomy Act 1832 legalized procurement of unclaimed bodies from public institutions for anatomical dissection at licensed Schools of Anatomy, effectively conferring the University of Sydney an exclusive license until ...
Rebekah A. Jenkin, Kevin A. Keay
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Endoscopic Resection of Exostosis at the Medial Border of Scapula

open access: yesArthroscopy Techniques, EarlyView.
Abstract Scapular exostoses are rare, and ventral lesions are more common than dorsal lesions. Scapular exostoses can cause symptoms including pain and mechanical crepitus due to scapulothoracic bursitis, decreased active range of motion, “pseudowinging” of the scapula and snapping scapula.
Tun Hing Lui, Florence Ou Suet Pang
wiley   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink   +9 more
wiley   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson   +22 more
wiley   +1 more source

‘Let's talk about the weather’: The activist curriculum and global climate change education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Activist movements have garnered significant global attention on a range of sustainability issues, often involving collectives of citizens coming together. Invoked is the idea of citizens informed to act, emerging not from a common‐sense understanding of everyday life, but rather from a deep political understanding of the world—one that is ...
Richard Pountney
wiley   +1 more source

Relational and feminist pedagogic approaches for developing engagement and inclusion of girls at risk of exclusion in England

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper highlights the inclusive potential of relational and feminist pedagogic strategies in education, focusing on girls at risk of exclusion. Girls in England are less likely than boys to be suspended or permanently excluded from school, but numbers are increasing.
Juliette Wilson‐Thomas   +3 more
wiley   +1 more source

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