Results 131 to 140 of about 6,330 (184)
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Depletion of florfenicol and florfenicol amine residues in chicken eggs
British Poultry Science, 20141. The aim of this study was to develop a suitable method for the analysis of florfenicol (FF) and its metabolite florfenicol amine (FFA) in chicken eggs and to determine FF and FFA residue depletion in eggs of laying hens. 2. The analytes were extracted from yolk, albumen and whole egg by phosphate buffer and ethyl acetate.
A, Filazi +4 more
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Pharmacokinetics of florfenicol and florfenicol‐amine after intravenous administration in sheep
Journal of Veterinary Pharmacology and Therapeutics, 2011Florfenicol (FFC) is a broad spectrum antibacterial agent that is structurally related to chloramphenicol but differs from it by the presence of a para-methyl sulphonyl group instead of the p-nitro group and the presence of a fluorine atom instead of the hydroxyl group in the terminal primary alcohol function (EMEA, 2002).
C, Palma +5 more
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Pharmacokinetics of florfenicol and its major metabolite, florfenicol amine, in rabbits
Journal of Veterinary Pharmacology and Therapeutics, 2007The pharmacokinetics of florfenicol and its active metabolite florfenicol amine were investigated in rabbits after a single intravenous (i.v.) and oral (p.o.) administration of florfenicol at 20 mg/kg bodyweight. The plasma concentrations of florfenicol and florfenicol amine were determined simultaneously by an LC/MS method. After i.v.
B-K, Park +4 more
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Pharmacokinetics and tolerance of florfenicol in Equidae
Equine Veterinary Journal, 1996Summary Florfenicol was administered to horses and ponies at a dose rate of 22 mg/kg bwt by i.v., i.m. and oral routes. Following i.v. administration it had an elimination half‐life of 1.8 ± 0.9 h, a body clearance of 0.4 ± 0.11/h.kg and a volume of distribution at steady‐state of 0.7 ± 0.2 1/kg. It was highly bioavailable following i.
Q A, McKellar, K J, Varma
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Pharmacokinetics of Florfenicol and Its Metabolite Florfenicol Amine in Atlantic Salmon
Journal of Aquatic Animal Health, 1996Abstract The plasma pharmacokinetic profile of the antibacterial agent florfenicol was studied in Atlantic salmon Salmo salar in seawater. In a single-dose study, each fish was given 10 mg/kg body weight by intravenous (iv) injection or by oral gavage of feed coated with the drug.
Tor Einar Horsberg +2 more
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Pharmacokinetics of florfenicol and thiamphenicol in ducks
Journal of Veterinary Pharmacology and Therapeutics, 2018AbstractThe pharmacokinetics of florfenicol (FF) and thiamphenicol (TP) after single intravenous (IV) and oral (PO) administration was investigated in Mulard ducks. Both antibiotics were administered at a dose of 30 mg/kg body weight, and their concentrations in plasma samples were assayed using high‐performance liquid chromatography with ultraviolet ...
Marta Tikhomirov +3 more
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Pharmacokinetics of florfenicol in veal calves
Journal of Veterinary Pharmacology and Therapeutics, 1986Varma, K.J., Adams, P.E., Powers, T.E., Powers, J.D. & Lamendola, J.F. Pharmacokinetics of florfenicol in veal calves. J. vet. Pharmacol. Therap. 9, 412–425.The pharmacokinetic disposition of florfenicol was described in veal calves after administration of a single 22‐mg/kg dose intravenously, orally after a 12‐h fast and orally 5 min post feeding.
K J, Varma +4 more
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Journal of Immunological Methods, 2013
Thiamphenicol and florfenicol are antibacterial agents permitted for use as veterinary drugs in animals used for food production. However, as the EU has established maximum residue limits for both and the metabolite florfenicol amine, there is a requirement to monitor animal food products for their residues.
Fodey, Terence L. +6 more
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Thiamphenicol and florfenicol are antibacterial agents permitted for use as veterinary drugs in animals used for food production. However, as the EU has established maximum residue limits for both and the metabolite florfenicol amine, there is a requirement to monitor animal food products for their residues.
Fodey, Terence L. +6 more
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Food Additives & Contaminants: Part A, 2022
Some florfenicol (FF) metabolites have a strong binding affinity towards biomolecules in the edible tissues of some food animals. These bound FF residues cannot be extracted directly from edible tissues with organic solvents and are present in higher concentrations even than solvent extractable residues.
Xia, Li +7 more
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Some florfenicol (FF) metabolites have a strong binding affinity towards biomolecules in the edible tissues of some food animals. These bound FF residues cannot be extracted directly from edible tissues with organic solvents and are present in higher concentrations even than solvent extractable residues.
Xia, Li +7 more
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Journal of Veterinary Pharmacology and Therapeutics, 2006
The pharmacokinetics of florfenicol and its metabolite, florfenicol amine, was investigated after its intravenous (i.v.) and oral (p.o.) administration of 20 mg/kg of body weight in Korean catfish (Silurus asotus). After i.v. florfenicol injection (as a bolus), the terminal half‐life (t1/2), the volume of distribution at steady state (Vdss), and total ...
B-K, Park, J-H, Lim, M-S, Kim, H-I, Yun
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The pharmacokinetics of florfenicol and its metabolite, florfenicol amine, was investigated after its intravenous (i.v.) and oral (p.o.) administration of 20 mg/kg of body weight in Korean catfish (Silurus asotus). After i.v. florfenicol injection (as a bolus), the terminal half‐life (t1/2), the volume of distribution at steady state (Vdss), and total ...
B-K, Park, J-H, Lim, M-S, Kim, H-I, Yun
openaire +2 more sources