Results 111 to 120 of about 17,674 (302)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan   +8 more
wiley   +1 more source

Testing and Concentration of a Low Grade Gold Ore from Marysville, Montana [PDF]

open access: yes, 1942
The purpose of this thesis was to investigate and attempt to concentrate low grade cyanided tailings rejected from the old Montana Mining and milling Company\u27s mill situated 4 miles below the town of Marysville ...
White,, John B., Jr.
core   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

Sparse attention convolution-ViT model for working condition recognition in zinc flotation

open access: yes工程科学学报
Accurate recognition of working conditions can optimize the zinc flotation process and improve its efficiency. Traditionally, this recognition heavily relies on manual observations of froth appearance, a method prone to human error and subjective ...
Yue SU   +6 more
doaj   +1 more source

Oceanus. [PDF]

open access: yes, 2000
v. 42, no.
Woods Hole Oceanographic Institution.
core   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

Selective Deposition of Charged Droplets for Programmable and Rewritable Printing of Patterned Microstructure Arrays

open access: yesAdvanced Science, EarlyView.
A residual‐charge‐induced electric field control (SDREC) strategy enables the fabrication of patterned microstructure arrays with a resolution of 20 µm via the selective deposition of charged droplets. The resulting arrays exhibit reversible writing/erasing, optical encryption, and selective silver electrode formation, offering a versatile route to ...
Yuechen Pei   +8 more
wiley   +1 more source

Structural and mechanical design challenges of space shuttle solid rocket boosters separation and recovery subsystems [PDF]

open access: yes
The design of the space shuttle solid rocket booster (SRB) subsystems for reuse posed some unique and challenging design considerations. The separation of the SRBs from the cluster (orbiter and external tank) at 150,000 ft when the orbiter engines are ...
Runkle, R. E., Woodis, W. R.
core   +1 more source

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