In hyperuricemia, uric acid inhibits CCDC90B ubiquitination degradation by binding to it. Excessive CCDC90B induces mitochondrial calcium overload, leading to mitochondrial quality control imbalance and ultimately resulting in SLC senescence and decreased testosterone levels.
Jiayu Huang +8 more
wiley +1 more source
Protocol to determine in vitro lipid-protein interactions using liposome flotation assay. [PDF]
Khadayat K, House M, Tati V, Joshi AS.
europepmc +1 more source
Human iPSC‐Derived Vascularised Lung Organoids for Modelling COPD and Pulmonary Hypertension
Vascularised lung organoids (vLOs) that faithfully mimic human lung tissue architecture and disease pathology are critical for advancing pulmonary research but remain challenging to generate. Here, we developed a robust self‐organisation protocol to produce vLOs with cellular heterogeneity and functional vasculature. The engineered blood vessels within
Simin Jiang +14 more
wiley +1 more source
Comparative Analysis of Industrial Fused Magnesia from Natural and Flotation-Processed Magnesite: Associations Among CaO/SiO<sub>2</sub> Ratio, Silicate Phase Formation, and Microcracking. [PDF]
Wang C +5 more
europepmc +1 more source
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas +4 more
wiley +1 more source
Surface modification of carbon-based adsorbents derived from coal gasification slag for the efficient adsorption of trimethoprim. [PDF]
Yang Z, Liu J, Li Q.
europepmc +1 more source
Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice
Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan +8 more
wiley +1 more source
Development of a Methodology for Analyzing Microplastics in Sewage Treatment Plants. [PDF]
da Silva de Aquino I +4 more
europepmc +1 more source
A STUDY OF THE FUNCTIONS OF FLOTATION REAGENTS IN THE SOAP FLOTATION OF SCHEELITE AND WOLFRAMITE
YAMADA, Gaiti, ITO, Itiro, FUNAGOSI, Sin
openaire +1 more source

