Results 11 to 20 of about 26,306 (256)

Journaling: A More Mindful Approach to Researching a Mindfulness-Based Intervention in a Junior School

International Journal of Qualitative Methods, 2021
Mindfulness, often defined as present-moment awareness, has in recent years become a topic of multidisciplinary interest. This article addresses methodological issues for researching mindfulness and education.
Andrea Crawford, Edward Sellman, Stephen Joseph   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

What smartphone apps exist to support recovery from opioid use disorder? A content analysis of publicly available opioid-related smartphone apps

Addiction Science & Clinical Practice
Background An estimated 84,181 people died due to opioid overdose in 2022 alone [1]. Mobile technologies may offer an additional pathway to provide support to people seeking recovery from opioid use disorder (OUD).
Alivia Williamson, Behnam Heydarshahi, Diadora Finley-Abboud, Lili Massac, Lindsay Jacobson, Naicha Christophe, Judeline Joseph, Allison Futter, Susanne S. Hoeppner, Bettina B. Hoeppner   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Childhood experiences and adult community participation in secular and religious contexts in 22 countries

Scientific Reports
Participation in community groups (including both secular and religious groups) is associated with improved health, well-being, and societal cohesion.
Ying Chen, Brendan W. Case, Katelyn N. G. Long, Robert Woodberry, Eric S. Kim, R. Noah Padgett, Byron R. Johnson, Tyler J. VanderWeele   +7 more
doaj   +1 more source

Flourishing Fashion: An Interpretive Phenomenological Analysis of the Experience of Wearing a Happy Outfit

Fashion Studies, 2018
Little research has been conducted into the relationship between fashion and psychology, even less on how individuals create wellbeing through appearance and clothing.
Rebecca Smith, Julia Yates
doaj   +1 more source

Traditional male circumcision and the risk for HIV transmission among men: a systematic review

BMJ Open, 2023
Objectives To synthesise evidence to determine whether, in contrast to medical male circumcision, traditional male circumcision (TMC) practices may contribute to HIV transmission and what the impacts of TMC are on the initiates, their families and ...
Gregorius Abanit Asa, Nelsensius Klau Fauk, Paul Russell Ward   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Community participation in secular and religious contexts across sociodemographic groups in 22 countries

Scientific Reports
In an increasingly fragmented and isolated world, community participation remains an essential source of social connection. However, how community participation varies across countries and sociodemographic groups remains unclear.
Ying Chen, Brendan W. Case, Katelyn N. G. Long, Robert D. Woodberry, Eric S. Kim, R. Noah Padgett, Byron R. Johnson, Tyler J. VanderWeele   +7 more
doaj   +1 more source